Botanical compounds

Effects on major eye diseases

Tuan Phat Huynh, Shivani N. Mann, Nawajes Mandal

Research output: Contribution to journalReview article

17 Citations (Scopus)

Abstract

Botanical compounds have been widely used throughout history as cures for various diseases and ailments. Many of these compounds exhibit strong antioxidative, anti-inflammatory, and antiapoptotic properties. These are also common damaging mechanisms apparent in several ocular diseases, including age-related macular degeneration (AMD), glaucoma, diabetic retinopathy, cataract, and retinitis pigmentosa. In recent years, there have been many epidemiological and clinical studies that have demonstrated the beneficial effects of plant-derived compounds, such as curcumin, lutein and zeaxanthin, danshen, ginseng, and many more, on these ocular pathologies. Studies in cell cultures and animal models showed promising results for their uses in eye diseases. While there are many apparent significant correlations, further investigation is needed to uncover the mechanistic pathways of these botanical compounds in order to reach widespread pharmaceutical use and provide noninvasive alternatives for prevention and treatments of the major eye diseases.

Original languageEnglish (US)
Article number549174
JournalEvidence-based Complementary and Alternative Medicine
Volume2013
DOIs
StatePublished - Jul 19 2013

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Eye Diseases
Salvia miltiorrhiza
Lutein
Panax
Curcumin
Retinitis Pigmentosa
Macular Degeneration
Phytochemicals
Diabetic Retinopathy
Glaucoma
Cataract
Epidemiologic Studies
Anti-Inflammatory Agents
Animal Models
Cell Culture Techniques
History
Pathology
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Complementary and alternative medicine

Cite this

Botanical compounds : Effects on major eye diseases. / Huynh, Tuan Phat; Mann, Shivani N.; Mandal, Nawajes.

In: Evidence-based Complementary and Alternative Medicine, Vol. 2013, 549174, 19.07.2013.

Research output: Contribution to journalReview article

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