Brief behavioral activation and problem-solving therapy for depressed breast cancer patients

Randomized trial

Derek R. Hopko, Maria E.A. Armento, Sarah M.C. Robertson, Marlena M. Ryba, John P. Carvalho, Lindsey K. Colman, Christen Mullane, Michael Gawrysiak, John Bell, James K. McNulty, Carl W. Lejuez

Research output: Contribution to journalArticle

93 Citations (Scopus)

Abstract

Objective: Major depression is the most common psychiatric disorder among breast cancer patients and is associated with substantial impairment. Although some research has explored the utility of psychotherapy with breast cancer patients, only 2 small trials have investigated the potential benefits of behavior therapy among patients with well-diagnosed depression. Method: In a primarily Caucasian, well-educated sample of women (age = 55.4 years, SD = 11.9) diagnosed with breast cancer and major depression (n = 80), this study was a randomized clinical trial testing the efficacy of 8 sessions of behavioral activation treatment for depression (BATD) compared to problem-solving therapy. Primary outcome measures assessed depression, environmental reward, anxiety, quality of life, social support, and medical outcomes. Results: Across both treatments, results revealed strong treatment integrity, excellent patient satisfaction with treatment protocols, and low patient attrition (19). Intent-to-treat analyses suggested both treatments were efficacious, with both evidencing significant pre-post treatment gains across all outcome measures. Across both treatments, gains were associated with strong effect sizes, and based on response and remission criteria, a reliable change index, and numbers-needed-to-treat analyses, approximately of patients exhibited clinically significant improvement. No significant group differences were found at posttreatment. Treatment gains were maintained at 12-month follow-up, with some support for stronger maintenance of gains in the BATD group. Conclusions: BATD and problem-solving interventions represent practical interventions that may improve psychological outcomes and quality of life among depressed breast cancer patients. Study limitations and future research directions are discussed.

Original languageEnglish (US)
Pages (from-to)834-849
Number of pages16
JournalJournal of Consulting and Clinical Psychology
Volume79
Issue number6
DOIs
StatePublished - Dec 1 2011
Externally publishedYes

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Breast Neoplasms
Depression
Therapeutics
Quality of Life
Outcome Assessment (Health Care)
Problem Behavior
Activation
Breast Cancer
Problem Solving
Cancer Patients
Therapy
Numbers Needed To Treat
Behavior Therapy
Clinical Protocols
Patient Satisfaction
Reward
Psychotherapy
Social Support
Psychiatry
Anxiety

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health

Cite this

Hopko, D. R., Armento, M. E. A., Robertson, S. M. C., Ryba, M. M., Carvalho, J. P., Colman, L. K., ... Lejuez, C. W. (2011). Brief behavioral activation and problem-solving therapy for depressed breast cancer patients: Randomized trial. Journal of Consulting and Clinical Psychology, 79(6), 834-849. https://doi.org/10.1037/a0025450

Brief behavioral activation and problem-solving therapy for depressed breast cancer patients : Randomized trial. / Hopko, Derek R.; Armento, Maria E.A.; Robertson, Sarah M.C.; Ryba, Marlena M.; Carvalho, John P.; Colman, Lindsey K.; Mullane, Christen; Gawrysiak, Michael; Bell, John; McNulty, James K.; Lejuez, Carl W.

In: Journal of Consulting and Clinical Psychology, Vol. 79, No. 6, 01.12.2011, p. 834-849.

Research output: Contribution to journalArticle

Hopko, DR, Armento, MEA, Robertson, SMC, Ryba, MM, Carvalho, JP, Colman, LK, Mullane, C, Gawrysiak, M, Bell, J, McNulty, JK & Lejuez, CW 2011, 'Brief behavioral activation and problem-solving therapy for depressed breast cancer patients: Randomized trial', Journal of Consulting and Clinical Psychology, vol. 79, no. 6, pp. 834-849. https://doi.org/10.1037/a0025450
Hopko, Derek R. ; Armento, Maria E.A. ; Robertson, Sarah M.C. ; Ryba, Marlena M. ; Carvalho, John P. ; Colman, Lindsey K. ; Mullane, Christen ; Gawrysiak, Michael ; Bell, John ; McNulty, James K. ; Lejuez, Carl W. / Brief behavioral activation and problem-solving therapy for depressed breast cancer patients : Randomized trial. In: Journal of Consulting and Clinical Psychology. 2011 ; Vol. 79, No. 6. pp. 834-849.
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