Bronchodilator effect of terbutaline aerosol in asthmatic

comparison of two spacer devices.

Rajiv Dhand, D. S. Sethi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The degree of bronchodilation achieved with aerosolised bronchodilators may partly depend on correct usage of a particular inhaler device. The effect of two puffs of 0.25 mg each of terbutaline aerosol using either of two spacer devices--a tube spacer and conical spacer with inhalation valve (Nebuhaler)--in a randomised manner were compared in 20 patients with bronchial asthma. All participants (11 male, 9 female) aged 16 to 50 years had clinically stable baseline airway obstruction responsive to bronchodilators. The maximum per cent increase of PEFR and FEV1 were significantly higher after inhalation via Nebuhaler than tube spacer (44.93 +/- 21.15% vs 26.67 +/- 13.17%; 74.0 +/- 17.87 vs 47.65 +/- 15.74% respectively, p less than 0.01). The increase noted at each time interval was significantly higher and more sustained with Nebuhaler. In terms of bronchodilator effect Nebuhaler had definite advantage over tube spacer in our study. There were no significant changes in pulse rate nor in blood pressure.

Original languageEnglish (US)
Pages (from-to)101-106
Number of pages6
JournalThe Indian journal of chest diseases & allied sciences
Volume32
Issue number2
StatePublished - Jan 1 1990
Externally publishedYes

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Inhalation Spacers
Terbutaline
Bronchodilator Agents
Aerosols
Equipment and Supplies
Peak Expiratory Flow Rate
Nebulizers and Vaporizers
Airway Obstruction
Inhalation
Asthma
Heart Rate
Blood Pressure

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Bronchodilator effect of terbutaline aerosol in asthmatic : comparison of two spacer devices. / Dhand, Rajiv; Sethi, D. S.

In: The Indian journal of chest diseases & allied sciences, Vol. 32, No. 2, 01.01.1990, p. 101-106.

Research output: Contribution to journalArticle

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