Calcium and phosphorous in pediatric parenteral nutrition

Katherine E. Marks, Catherine Herrington

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Calcium (Ca) and phosphorus (P) are essential for various systemic functions, including bone mineralization. Adequate provision of Ca and P in pediatric parenteral nutrition (PN) solutions is necessary for skeletal growth and for the prevention of metabolic bone disease. The provision of adequate doses of Ca and P in pediatric PN solutions is complicated by the increased needs in preterm and term infants, solubility limitations, and venous access. Clinicians should be aware of the evidence that supports the optimal use of Ca and P in pediatric PN solutions, including studies that have evaluated dosing and solubility. The aim of this article is to review relevant literature and practices for the use of these two minerals in pediatric PN solutions. The vitamin D endocrine system, a critical component for Ca homeostasis and bone mineralization, is discussed, as well as clinical manifestations of metabolic bone disease and methods for its prevention, assessment, and treatment in pediatric patients receiving PN.

Original languageEnglish (US)
Pages (from-to)432-446
Number of pages15
JournalJournal of Pharmacy Practice
Volume17
Issue number6
DOIs
StatePublished - Dec 1 2004

Fingerprint

Parenteral Nutrition Solutions
Parenteral Nutrition
Pediatrics
Calcium
Physiologic Calcification
Metabolic Bone Diseases
Solubility
Endocrine System
Premature Infants
Vitamin D
Phosphorus
Minerals
Homeostasis
Growth

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)

Cite this

Calcium and phosphorous in pediatric parenteral nutrition. / Marks, Katherine E.; Herrington, Catherine.

In: Journal of Pharmacy Practice, Vol. 17, No. 6, 01.12.2004, p. 432-446.

Research output: Contribution to journalReview article

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