Cardiopulmonary exercise testing in congestive heart failure

Patricia A. McElroy, Joseph S. Janicki, Karl Weber

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Cardiopulmonary exercise testing includes the monitoring of respiratory gases and airflow to determine oxygen uptake, carbon dioxide (CO2) production, respiratory rate, tidal volume, and minute ventilation during a graded maximal exercise test. A plateau in oxygen uptake, which occurs despite an increase in work load, and which is termed maximal oxygen uptake (V̇O2 max), correlates with the maximal exercise cardiac output and can therefore be used to grade the severity of heart failure. The anaerobic threshold occurs at 60 to 70% of V̇O2 max and is another indicator of the severity of heart failure and, when attained, indicates that the patient is close to performing a maximal test. We have found V̇O2 max and anaerobic threshold to be objective measures of efficacy of both investigational and noninvestigational therapy in patients with heart failure. A pulmonary limitation to exercise can be identified by the failure to attain anaerobic threshold or V̇O2 max, as well as exhaustion of the ventilatory reserve, as estimated by maximal voluntary ventilation. Thus, cardiopulmonary exercise testing can be used to (1) grade the severity of heart failure, (2) objectively follow the response to therapy, and (3) differentiate a cardiac from a pulmonary limitation to exercise.

Original languageEnglish (US)
Pages (from-to)35A-40A
JournalThe American journal of cardiology
Volume62
Issue number2
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

Fingerprint

Anaerobic Threshold
Heart Failure
Exercise
Oxygen
Maximal Voluntary Ventilation
Pulmonary Ventilation
Lung
Investigational Therapies
Tidal Volume
Respiratory Rate
Workload
Exercise Test
Carbon Dioxide
Cardiac Output
Ventilation
Gases
Therapeutics

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Cardiopulmonary exercise testing in congestive heart failure. / McElroy, Patricia A.; Janicki, Joseph S.; Weber, Karl.

In: The American journal of cardiology, Vol. 62, No. 2, 01.01.1988, p. 35A-40A.

Research output: Contribution to journalArticle

McElroy, Patricia A. ; Janicki, Joseph S. ; Weber, Karl. / Cardiopulmonary exercise testing in congestive heart failure. In: The American journal of cardiology. 1988 ; Vol. 62, No. 2. pp. 35A-40A.
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