Case-control study of armadillo contact and Hansen's disease

Brychan M. Clark, Clinton K. Murray, Lynn L. Horvath, Gregory A. Deye, Mark Rasnake, Robert N. Longfield

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Hansen's disease (HD) continues to have worldwide impact despite efforts to eradicate the disease. Although a definitive transmission mode has not been identified, data supports an association between HD and contact with the nine-banded armadillo. We conducted a case-control study of 28 HD patients to determine if there is an association between armadillo exposure and HD. There was no association between HD and place of birth or having hunted, consumed, or had direct or indirect contact with deer, birds, or squirrels. Univariate analysis showed that residence in Mexico (P = 0.001), hunting rabbits (P = 0.04), cleaning rabbits (P < 0.001), and armadillo exposure from hunting (P = 0.005), cleaning (P = 0.004), consuming (P = 0.002) them, or having direct armadillo contact (P = 0.017) were associated with HD. Multivariate analysis showed that eating armadillos (P = 0.039, odds ratio [OR] = 3.65, 95% confidence interval [CI] = 1.07-12.4), cleaning rabbits (P = 0.018, OR = 4.08, 95% CI = 1.27-13.1), and having lived in Mexico (P = 0.006, OR = 24.9, 95% CI = 2.52-245) were associated with HD.

Original languageEnglish (US)
Pages (from-to)962-967
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume78
Issue number6
StatePublished - Jun 1 2008

Fingerprint

Armadillos
Leprosy
Case-Control Studies
Odds Ratio
Confidence Intervals
Rabbits
Mexico
Sciuridae
Deer
Birds
Multivariate Analysis
Eating

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Virology
  • Infectious Diseases

Cite this

Clark, B. M., Murray, C. K., Horvath, L. L., Deye, G. A., Rasnake, M., & Longfield, R. N. (2008). Case-control study of armadillo contact and Hansen's disease. American Journal of Tropical Medicine and Hygiene, 78(6), 962-967.

Case-control study of armadillo contact and Hansen's disease. / Clark, Brychan M.; Murray, Clinton K.; Horvath, Lynn L.; Deye, Gregory A.; Rasnake, Mark; Longfield, Robert N.

In: American Journal of Tropical Medicine and Hygiene, Vol. 78, No. 6, 01.06.2008, p. 962-967.

Research output: Contribution to journalArticle

Clark, BM, Murray, CK, Horvath, LL, Deye, GA, Rasnake, M & Longfield, RN 2008, 'Case-control study of armadillo contact and Hansen's disease', American Journal of Tropical Medicine and Hygiene, vol. 78, no. 6, pp. 962-967.
Clark BM, Murray CK, Horvath LL, Deye GA, Rasnake M, Longfield RN. Case-control study of armadillo contact and Hansen's disease. American Journal of Tropical Medicine and Hygiene. 2008 Jun 1;78(6):962-967.
Clark, Brychan M. ; Murray, Clinton K. ; Horvath, Lynn L. ; Deye, Gregory A. ; Rasnake, Mark ; Longfield, Robert N. / Case-control study of armadillo contact and Hansen's disease. In: American Journal of Tropical Medicine and Hygiene. 2008 ; Vol. 78, No. 6. pp. 962-967.
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