Causes and consequences of systemic venous hypertension

Basil M. Paulus, Sheharyar Ali, Ayhan A. Zia, Ahmad Munir, Richard C. Davis, Charles M. Mansbach, W. Chapman Smith, Karl Weber

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

The causes of systemic venous hypertension (SVHT) include cardiac- and circulatory-related factors, whereas its consequences include the congestion of hepatic, splanchnic, and peripheral circulations, which contribute significantly to the clinical congestive heart failure syndrome. Based on a disequilibrium in hydrostatic and oncotic pressures, the increased filtration and formation of interstitial fluid at these sites with an accompanying increase in lymph flow mandates an increment in lymphatic drainage to protect against such congestion and the appearance of edema and ascites. However, lymph flow via the thoracic duct into systemic veins is opposed by elevations in central venous pressure. Various management strategies have the potential to prevent and/or correct SVHT. The case of a 54-year-old man with a dilated cardiomyopathy who presented with decompensated biventricular failure, expressed as anasarca and ascites, is used to illustrate the importance of SVHT.

Original languageEnglish (US)
Pages (from-to)489-497
Number of pages9
JournalAmerican Journal of the Medical Sciences
Volume336
Issue number6
DOIs
StatePublished - Jan 1 2008

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Lymph
Hypertension
Ascites
Edema
Splanchnic Circulation
Thoracic Duct
Central Venous Pressure
Hydrostatic Pressure
Extracellular Fluid
Dilated Cardiomyopathy
Drainage
Veins
Heart Failure
Liver

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Paulus, B. M., Ali, S., Zia, A. A., Munir, A., Davis, R. C., Mansbach, C. M., ... Weber, K. (2008). Causes and consequences of systemic venous hypertension. American Journal of the Medical Sciences, 336(6), 489-497. https://doi.org/10.1097/MAJ.0b013e318176abe9

Causes and consequences of systemic venous hypertension. / Paulus, Basil M.; Ali, Sheharyar; Zia, Ayhan A.; Munir, Ahmad; Davis, Richard C.; Mansbach, Charles M.; Smith, W. Chapman; Weber, Karl.

In: American Journal of the Medical Sciences, Vol. 336, No. 6, 01.01.2008, p. 489-497.

Research output: Contribution to journalReview article

Paulus, BM, Ali, S, Zia, AA, Munir, A, Davis, RC, Mansbach, CM, Smith, WC & Weber, K 2008, 'Causes and consequences of systemic venous hypertension', American Journal of the Medical Sciences, vol. 336, no. 6, pp. 489-497. https://doi.org/10.1097/MAJ.0b013e318176abe9
Paulus BM, Ali S, Zia AA, Munir A, Davis RC, Mansbach CM et al. Causes and consequences of systemic venous hypertension. American Journal of the Medical Sciences. 2008 Jan 1;336(6):489-497. https://doi.org/10.1097/MAJ.0b013e318176abe9
Paulus, Basil M. ; Ali, Sheharyar ; Zia, Ayhan A. ; Munir, Ahmad ; Davis, Richard C. ; Mansbach, Charles M. ; Smith, W. Chapman ; Weber, Karl. / Causes and consequences of systemic venous hypertension. In: American Journal of the Medical Sciences. 2008 ; Vol. 336, No. 6. pp. 489-497.
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