Cellular mechanics in human blood eosinophils and leukotriene C 4 synthesis

Christopher M. Waters, Ushma Savla, Pam Kuagoolwongse, Peter H.S. Sporn

Research output: Contribution to journalConference article

Abstract

Cellular mechanics in human blood eosinophils and leukotriene C 4 (LTC4) synthesis were studied. The inhibition of LTC4 synthesis was sustained for 2 hours after initial stretch treatment. It was demonstrated that the cyclic mechanical strain inhibits LTC4 synthesis by adherent eosinophils in a frequency-dependent and relaxation time-dependent manner.

Original languageEnglish (US)
Pages (from-to)635-636
Number of pages2
JournalAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume50
StatePublished - Dec 1 2001

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Mechanics
Blood
Relaxation time

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Cellular mechanics in human blood eosinophils and leukotriene C 4 synthesis. / Waters, Christopher M.; Savla, Ushma; Kuagoolwongse, Pam; Sporn, Peter H.S.

In: American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, Vol. 50, 01.12.2001, p. 635-636.

Research output: Contribution to journalConference article

Waters, Christopher M. ; Savla, Ushma ; Kuagoolwongse, Pam ; Sporn, Peter H.S. / Cellular mechanics in human blood eosinophils and leukotriene C 4 synthesis. In: American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 2001 ; Vol. 50. pp. 635-636.
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