Centrifugal intensity and duration as countermeasures to soleus muscle atrophy

D. S. D'Aunno, Donald Thomason, F. W. Booth

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Mechanical acceleration is a countermeasure that may be employed to prevent atrophy of slow-twitch muscle during non-weight bearing. In the present study, daily centrifugation of rats for different durations (1 or 2 h) and at different gravitational intensities (1.5 or 2.6 G) was used to test whether mechanical acceleration could ameliorate the atrophy of the soleus muscle induced by non-weight bearing (tail-traction model). The soleus muscle atrophied 32% during 7 days of non-weight bearing without countermeasures. Centrifugation treatment did not completely prevent atrophy relative to precontrol wet weight of the soleus muscle. Non-weight-bearing groups receiving 2-h daily treatments of 1, 1.5, or 2.6 G had 48, 56, and 65%, respectively, of the atrophy observed in the non-weight-bearing-only group compared with the precontrol group. No evidence was obtained that centrifugation at 2.6 G was more effective than exposure to 1 or 1.5 G as a counter-measure to non-weight-bearing-induced atrophy of the soleus muscle.

Original languageEnglish (US)
Pages (from-to)1387-1389
Number of pages3
JournalJournal of Applied Physiology
Volume69
Issue number4
StatePublished - 1990
Externally publishedYes

Fingerprint

Muscular Atrophy
Atrophy
Skeletal Muscle
Centrifugation
Traction
Tail
Weights and Measures
Muscles
Therapeutics

All Science Journal Classification (ASJC) codes

  • Endocrinology
  • Physiology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Centrifugal intensity and duration as countermeasures to soleus muscle atrophy. / D'Aunno, D. S.; Thomason, Donald; Booth, F. W.

In: Journal of Applied Physiology, Vol. 69, No. 4, 1990, p. 1387-1389.

Research output: Contribution to journalArticle

@article{417857e57a914e9284c59ddf4b7c878f,
title = "Centrifugal intensity and duration as countermeasures to soleus muscle atrophy",
abstract = "Mechanical acceleration is a countermeasure that may be employed to prevent atrophy of slow-twitch muscle during non-weight bearing. In the present study, daily centrifugation of rats for different durations (1 or 2 h) and at different gravitational intensities (1.5 or 2.6 G) was used to test whether mechanical acceleration could ameliorate the atrophy of the soleus muscle induced by non-weight bearing (tail-traction model). The soleus muscle atrophied 32{\%} during 7 days of non-weight bearing without countermeasures. Centrifugation treatment did not completely prevent atrophy relative to precontrol wet weight of the soleus muscle. Non-weight-bearing groups receiving 2-h daily treatments of 1, 1.5, or 2.6 G had 48, 56, and 65{\%}, respectively, of the atrophy observed in the non-weight-bearing-only group compared with the precontrol group. No evidence was obtained that centrifugation at 2.6 G was more effective than exposure to 1 or 1.5 G as a counter-measure to non-weight-bearing-induced atrophy of the soleus muscle.",
author = "D'Aunno, {D. S.} and Donald Thomason and Booth, {F. W.}",
year = "1990",
language = "English (US)",
volume = "69",
pages = "1387--1389",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "4",

}

TY - JOUR

T1 - Centrifugal intensity and duration as countermeasures to soleus muscle atrophy

AU - D'Aunno, D. S.

AU - Thomason, Donald

AU - Booth, F. W.

PY - 1990

Y1 - 1990

N2 - Mechanical acceleration is a countermeasure that may be employed to prevent atrophy of slow-twitch muscle during non-weight bearing. In the present study, daily centrifugation of rats for different durations (1 or 2 h) and at different gravitational intensities (1.5 or 2.6 G) was used to test whether mechanical acceleration could ameliorate the atrophy of the soleus muscle induced by non-weight bearing (tail-traction model). The soleus muscle atrophied 32% during 7 days of non-weight bearing without countermeasures. Centrifugation treatment did not completely prevent atrophy relative to precontrol wet weight of the soleus muscle. Non-weight-bearing groups receiving 2-h daily treatments of 1, 1.5, or 2.6 G had 48, 56, and 65%, respectively, of the atrophy observed in the non-weight-bearing-only group compared with the precontrol group. No evidence was obtained that centrifugation at 2.6 G was more effective than exposure to 1 or 1.5 G as a counter-measure to non-weight-bearing-induced atrophy of the soleus muscle.

AB - Mechanical acceleration is a countermeasure that may be employed to prevent atrophy of slow-twitch muscle during non-weight bearing. In the present study, daily centrifugation of rats for different durations (1 or 2 h) and at different gravitational intensities (1.5 or 2.6 G) was used to test whether mechanical acceleration could ameliorate the atrophy of the soleus muscle induced by non-weight bearing (tail-traction model). The soleus muscle atrophied 32% during 7 days of non-weight bearing without countermeasures. Centrifugation treatment did not completely prevent atrophy relative to precontrol wet weight of the soleus muscle. Non-weight-bearing groups receiving 2-h daily treatments of 1, 1.5, or 2.6 G had 48, 56, and 65%, respectively, of the atrophy observed in the non-weight-bearing-only group compared with the precontrol group. No evidence was obtained that centrifugation at 2.6 G was more effective than exposure to 1 or 1.5 G as a counter-measure to non-weight-bearing-induced atrophy of the soleus muscle.

UR - http://www.scopus.com/inward/record.url?scp=0025129711&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025129711&partnerID=8YFLogxK

M3 - Article

VL - 69

SP - 1387

EP - 1389

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 4

ER -