Cerebrovascular hemodynamic inefficiency of premature ventricular contractions

Marc Malkoff, Camilo R. Gomez, Geraldine Myles, Salvador Cruz-Flores

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Transcranial Doppler (TCD) measurements of middle cerebral artery (MCA) blood flow velocities were recorded and synchronized with electrocardiographic (EKG) recordings in 52 EKG/TCD complexes in 4 patients. Thirty-seven normal sinus beats and 13 conductive and 2 nonconductive premature ventricular contractions (PVCs) were examined. Mean velocities averaged 45 ± 4 cm/sec for normal sinus rhythm (NSR) vs 26 ± 4 cm/sec in the PVC group (P = 0.007). Peak systolic velocities averaged 74 ± 6 cm/sec for the NSR and 45 ± 7 cm/sec in the PVC group (P = 0.016). The latency between the QRS complexes and corresponding TCD wave forms (QRS-SU) averaged 0.12 ± 0.03 sec in NSR and 0.17 ± 0.04 sec for the PVC group (P < 0.001). In addition, QRS-SU was inversely related to all velocities. PVCs appeared to be less hemodynamically efficient than NSR. The lower blood flow velocities and increased QRS-SU may result from lower stroke volume and delayed ventricular contraction associated with the aberrant QRS complex.

Original languageEnglish (US)
Pages (from-to)51-56
Number of pages6
JournalAngiology
Volume47
Issue number1
DOIs
StatePublished - Jan 1 1996
Externally publishedYes

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Ventricular Premature Complexes
Hemodynamics
Blood Flow Velocity
Cerebrovascular Circulation
Electrocardiography
Middle Cerebral Artery
Stroke Volume

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Cerebrovascular hemodynamic inefficiency of premature ventricular contractions. / Malkoff, Marc; Gomez, Camilo R.; Myles, Geraldine; Cruz-Flores, Salvador.

In: Angiology, Vol. 47, No. 1, 01.01.1996, p. 51-56.

Research output: Contribution to journalArticle

Malkoff, Marc ; Gomez, Camilo R. ; Myles, Geraldine ; Cruz-Flores, Salvador. / Cerebrovascular hemodynamic inefficiency of premature ventricular contractions. In: Angiology. 1996 ; Vol. 47, No. 1. pp. 51-56.
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