Cervical insufficiency

Are some cases fetal induced? a report of 2 cases

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Many causes for cervical insufficiency have been reported, including trauma, infections, irritants, and social factors. This report describes 2 separate cases of pregnancy loss caused by cervical insufficiency that appear to be pregnancy/fetus specific. CASES: Two unrelated patients had similar histories with 2 midgestation losses from cervical insufficiency that occurred before and after full-term deliveries. Both cases occurred in married, middle class women, and the fathers in each case were unchanged. No known factors associated with cervical insufficiency were present in either patient. The only variable that was different was the specific pregnancy. CONCLUSION: These 2 cases might suggest that the fetus and/or placenta may have produced some change that provoked painless cervical dilation. Whether this could be genomic, epigenetic, hormonal, metabolomic, or a combination of these factors is unknown, but further research in this area is needed.

Original languageEnglish (US)
Pages (from-to)473-475
Number of pages3
JournalJournal of Reproductive Medicine
Volume63
Issue number5
StatePublished - Oct 1 2018
Externally publishedYes

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Pregnancy
Fetus
Metabolomics
Irritants
Epigenomics
Fathers
Placenta
Dilatation
Wounds and Injuries
Infection
Research

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this

Cervical insufficiency : Are some cases fetal induced? a report of 2 cases. / Towers, Craig.

In: Journal of Reproductive Medicine, Vol. 63, No. 5, 01.10.2018, p. 473-475.

Research output: Contribution to journalArticle

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