Characterization of mechanisms of resistance to β-lactam antibiotics in methicillin-resistant strains of Staphylococcus saprophyticus

C. W. Stratton, Michael Gelfand, J. L. Gerberding, H. F. Chambers

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The resistance mechanisms of methicillin-resistant sttrains of Staphylococcus saprophyticus were characterized. Penicillin-binding protein (PBP) studies demonstrated an inducible PBP identical to PBP 2a in the membranes of these isolates. The amount of β-lactamase produced was minimal. PBP 2a is responsible for the methicillin resistance observed in these strains of S. saprophyticus.

Original languageEnglish (US)
Pages (from-to)1780-1782
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume34
Issue number9
DOIs
StatePublished - Jan 1 1990
Externally publishedYes

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Staphylococcus saprophyticus
Penicillin-Binding Proteins
Lactams
Methicillin Resistance
Anti-Bacterial Agents
Membranes

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Characterization of mechanisms of resistance to β-lactam antibiotics in methicillin-resistant strains of Staphylococcus saprophyticus. / Stratton, C. W.; Gelfand, Michael; Gerberding, J. L.; Chambers, H. F.

In: Antimicrobial Agents and Chemotherapy, Vol. 34, No. 9, 01.01.1990, p. 1780-1782.

Research output: Contribution to journalArticle

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