Circadian rhythm of suprachiasmatic nucleus neurons and its control to feeding centers in the rat hypothalamus

Y. Oomura, S. Shibata, Hitoshi Kita

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Circadian rhythm of suprachiasmatic nucleus (SCN) was studies using brain slice, and relations between optic nerve, ventromedial hypothalamic nucleus (VMH), lateral hypothalamic area (LHA), and SCN were studied in brain slice and anesthetized rat. Spontaneous SCN neural activity, measured as unit discharge rate, fluctuated in circadian cycles. Unit discharge rates in animals maintained in normal light-dark (L-D) schedules peaked during the day and neaped at night. In reversed L-D schedule, SCN activity also reversed so that peak still occurred during light phase of L-D cycle. Optic nerve stimulation facilitated SCN activity which in turn facilitated VMH neurons and inhibited LHA neurons. Neuronal effects on circadian rhythm of rat feeding behavior is discussed in the context of above results.

Original languageEnglish (US)
Pages (from-to)61-70
Number of pages10
JournalAdvances in the Biosciences
Volume41
Issue numberC
StatePublished - Dec 1 1982
Externally publishedYes

Fingerprint

Suprachiasmatic Nucleus
Circadian Rhythm
Hypothalamus
Lateral Hypothalamic Area
Neurons
Ventromedial Hypothalamic Nucleus
Optic Nerve
Light
Appointments and Schedules
Photoperiod
Brain
Feeding Behavior

Cite this

Circadian rhythm of suprachiasmatic nucleus neurons and its control to feeding centers in the rat hypothalamus. / Oomura, Y.; Shibata, S.; Kita, Hitoshi.

In: Advances in the Biosciences, Vol. 41, No. C, 01.12.1982, p. 61-70.

Research output: Contribution to journalArticle

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