Clinical approach to a patient presenting with muscle stiffness

Shameela N. Ahmed, Tulio Bertorini, Pushpa Narayanaswami, Kandasami Senthilkumar

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

SPS is a disorder that needs to be considered and recognized in patients presenting with muscle stiffness and spasms, because early diagnosis and appropriate treatment can substantially help the patient and prevent significant injuries and limitations that occur with the natural progression of the disease. A diagnosis of SPS should prompt investigation for thymoma and an occult malignancy, because SPS can be a paraneoplastic syndrome. SPS may be associated with other autoimmune diseases such as IDDM and Hashimoto's thyroiditis, and a work-up for these disorders is appropriate. Symptomatic treatment with benzodiazepines and other GABAergic medications is commonly used and immunomodulating therapy, especially IVIG, is beneficial.

Original languageEnglish (US)
Pages (from-to)150-160
Number of pages11
JournalJournal of Clinical Neuromuscular Disease
Volume4
Issue number3
DOIs
StatePublished - Mar 1 2003

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Muscles
Paraneoplastic Syndromes
Hashimoto Disease
Thymoma
Intravenous Immunoglobulins
Spasm
Benzodiazepines
Type 1 Diabetes Mellitus
Autoimmune Diseases
Disease Progression
Early Diagnosis
Therapeutics
Wounds and Injuries
Neoplasms

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Clinical approach to a patient presenting with muscle stiffness. / Ahmed, Shameela N.; Bertorini, Tulio; Narayanaswami, Pushpa; Senthilkumar, Kandasami.

In: Journal of Clinical Neuromuscular Disease, Vol. 4, No. 3, 01.03.2003, p. 150-160.

Research output: Contribution to journalReview article

Ahmed, Shameela N. ; Bertorini, Tulio ; Narayanaswami, Pushpa ; Senthilkumar, Kandasami. / Clinical approach to a patient presenting with muscle stiffness. In: Journal of Clinical Neuromuscular Disease. 2003 ; Vol. 4, No. 3. pp. 150-160.
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