Clinical experimentation with aerosol antibiotics: Current and future methods of administration

Paul Zarogoulidis, Ioannis Kioumis, Konstantinos Porpodis, Dionysios Spyratos, Kosmas Tsakiridis, Haidong Huang, Qiang Li, J. Turner, Robert Browning, Wolfgang Hohenforst-Schmidt, Konstantinos Zarogoulidis

Research output: Contribution to journalReview article

18 Citations (Scopus)

Abstract

Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed.

Original languageEnglish (US)
Pages (from-to)1115-1134
Number of pages20
JournalDrug Design, Development and Therapy
Volume7
DOIs
StatePublished - Oct 1 2013

Fingerprint

Aerosols
Anti-Bacterial Agents
Nanotechnology
Drug Design
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery

Cite this

Zarogoulidis, P., Kioumis, I., Porpodis, K., Spyratos, D., Tsakiridis, K., Huang, H., ... Zarogoulidis, K. (2013). Clinical experimentation with aerosol antibiotics: Current and future methods of administration. Drug Design, Development and Therapy, 7, 1115-1134. https://doi.org/10.2147/DDDT.S51303

Clinical experimentation with aerosol antibiotics : Current and future methods of administration. / Zarogoulidis, Paul; Kioumis, Ioannis; Porpodis, Konstantinos; Spyratos, Dionysios; Tsakiridis, Kosmas; Huang, Haidong; Li, Qiang; Turner, J.; Browning, Robert; Hohenforst-Schmidt, Wolfgang; Zarogoulidis, Konstantinos.

In: Drug Design, Development and Therapy, Vol. 7, 01.10.2013, p. 1115-1134.

Research output: Contribution to journalReview article

Zarogoulidis, P, Kioumis, I, Porpodis, K, Spyratos, D, Tsakiridis, K, Huang, H, Li, Q, Turner, J, Browning, R, Hohenforst-Schmidt, W & Zarogoulidis, K 2013, 'Clinical experimentation with aerosol antibiotics: Current and future methods of administration', Drug Design, Development and Therapy, vol. 7, pp. 1115-1134. https://doi.org/10.2147/DDDT.S51303
Zarogoulidis, Paul ; Kioumis, Ioannis ; Porpodis, Konstantinos ; Spyratos, Dionysios ; Tsakiridis, Kosmas ; Huang, Haidong ; Li, Qiang ; Turner, J. ; Browning, Robert ; Hohenforst-Schmidt, Wolfgang ; Zarogoulidis, Konstantinos. / Clinical experimentation with aerosol antibiotics : Current and future methods of administration. In: Drug Design, Development and Therapy. 2013 ; Vol. 7. pp. 1115-1134.
@article{ceaa0f1867e1481cbb9e0b7b57a7dd7b,
title = "Clinical experimentation with aerosol antibiotics: Current and future methods of administration",
abstract = "Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed.",
author = "Paul Zarogoulidis and Ioannis Kioumis and Konstantinos Porpodis and Dionysios Spyratos and Kosmas Tsakiridis and Haidong Huang and Qiang Li and J. Turner and Robert Browning and Wolfgang Hohenforst-Schmidt and Konstantinos Zarogoulidis",
year = "2013",
month = "10",
day = "1",
doi = "10.2147/DDDT.S51303",
language = "English (US)",
volume = "7",
pages = "1115--1134",
journal = "Drug Design, Development and Therapy",
issn = "1177-8881",
publisher = "Dove Medical Press Ltd.",

}

TY - JOUR

T1 - Clinical experimentation with aerosol antibiotics

T2 - Current and future methods of administration

AU - Zarogoulidis, Paul

AU - Kioumis, Ioannis

AU - Porpodis, Konstantinos

AU - Spyratos, Dionysios

AU - Tsakiridis, Kosmas

AU - Huang, Haidong

AU - Li, Qiang

AU - Turner, J.

AU - Browning, Robert

AU - Hohenforst-Schmidt, Wolfgang

AU - Zarogoulidis, Konstantinos

PY - 2013/10/1

Y1 - 2013/10/1

N2 - Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed.

AB - Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed.

UR - http://www.scopus.com/inward/record.url?scp=84885085487&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84885085487&partnerID=8YFLogxK

U2 - 10.2147/DDDT.S51303

DO - 10.2147/DDDT.S51303

M3 - Review article

C2 - 24115836

AN - SCOPUS:84885085487

VL - 7

SP - 1115

EP - 1134

JO - Drug Design, Development and Therapy

JF - Drug Design, Development and Therapy

SN - 1177-8881

ER -