Clinical features of peri-implant medication-related osteonecrosis of the jaw

Is there an association to peri-implantitis?

Matthias Troeltzsch, David Cagna, Philip Stähler, Florian Probst, Gabriele Kaeppler, Markus Troeltzsch, Michael Ehrenfeld, Sven Otto

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The purpose of this study was to examine the behavior of dental implants in patients diagnosed with MRONJ and to analyze the characteristics of peri-implant MRONJ. It was hypothesized that peri-implant parameters are not associated with peri-implant MRONJ. A retrospective study design was selected to address the research purpose. Patients with confirmed MRONJ and the simultaneous presence of dental implants who presented between 2010 and 2016 served as the study cohort. Predefined inclusion and exclusion criteria were applied. Demographic, clinical and radiological data were collected and analyzed statistically with respect to the variable scale (significance level p ≤ 0.05). The study sample was composed of 34 patients (female: 16; male: 18; average age: 70.6 years) with a total of 117 dental implants the majority of whom had received antiresorptive drug therapy within oncologic treatment protocols. Peri-implant MRONJ occurred in 15 patients (44%). Signs of peri-implantitis (present around 46/117 implants; 39%) appeared to be associated with the occurrence of peri-implant MRONJ. Patients receiving antiresorptive drugs in high doses seem to be at risk of developing MRONJ in the vicinity of dental implants. Peri-implantitis may be associated with the etiology of peri-implant MRONJ.

Original languageEnglish (US)
Pages (from-to)1945-1951
Number of pages7
JournalJournal of Cranio-Maxillofacial Surgery
Volume44
Issue number12
DOIs
StatePublished - Dec 1 2016

Fingerprint

Peri-Implantitis
Osteonecrosis
Jaw
Dental Implants
Bone Density Conservation Agents
Clinical Protocols
Cohort Studies
Retrospective Studies
Demography
Drug Therapy
Research

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

Cite this

Clinical features of peri-implant medication-related osteonecrosis of the jaw : Is there an association to peri-implantitis? / Troeltzsch, Matthias; Cagna, David; Stähler, Philip; Probst, Florian; Kaeppler, Gabriele; Troeltzsch, Markus; Ehrenfeld, Michael; Otto, Sven.

In: Journal of Cranio-Maxillofacial Surgery, Vol. 44, No. 12, 01.12.2016, p. 1945-1951.

Research output: Contribution to journalArticle

Troeltzsch, Matthias ; Cagna, David ; Stähler, Philip ; Probst, Florian ; Kaeppler, Gabriele ; Troeltzsch, Markus ; Ehrenfeld, Michael ; Otto, Sven. / Clinical features of peri-implant medication-related osteonecrosis of the jaw : Is there an association to peri-implantitis?. In: Journal of Cranio-Maxillofacial Surgery. 2016 ; Vol. 44, No. 12. pp. 1945-1951.
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