Clinical utility of FDG-PET in detecting head and neck tumors

A comparison of diagnostic methods and modalities

Karl Hubner, Joseph A. Thie, Gary T. Smith, Alex C. Chan, Patricia S. Fernandez, James Mccoy

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Positron emission tomography (PET) using F-18-fluoro-2-deoxy-d-glucose(F-18-FDG) is gaining acceptance as a useful imaging method for head and neck tumors. Results of 59 PET scans done on 45 patients with head and neck tumors were evaluated retrospectively. Thirty-six patients had prior treatment consisting of surgery, radiation therapy, chemotherapy, or a combination of these modalities. PET results were compared to computed tomography (CT [N = 38]) and magnetic resonance imaging (MRI [N = 14]) results and validated by histologic findings or survival. PET identified 36 out of 37 tumors (sensitivity 97%) and 18 of 22 benign processes (specificity 82%). Tumor was ruled out in 18 out of 19 patients. For CT, the sensitivity was 80% (20/25) and specificity was 31% (4/13). FDG-PET facilitates differentiation of recurrent head and neck tumors from treatment related changes sometimes difficult to characterize by CT or MRI and may have a significant impact on the management of patients reducing morbidity and costs.

Original languageEnglish (US)
Pages (from-to)7-16
Number of pages10
JournalClinical Positron Imaging (Netherlands)
Volume3
Issue number1
DOIs
StatePublished - Jan 1 2000

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Positron-Emission Tomography
Neck
Head
Neoplasms
Radiotherapy
Tomography
Magnetic Resonance Imaging
Morbidity
Costs and Cost Analysis
Glucose
Drug Therapy
Survival
Therapeutics

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Clinical utility of FDG-PET in detecting head and neck tumors : A comparison of diagnostic methods and modalities. / Hubner, Karl; Thie, Joseph A.; Smith, Gary T.; Chan, Alex C.; Fernandez, Patricia S.; Mccoy, James.

In: Clinical Positron Imaging (Netherlands), Vol. 3, No. 1, 01.01.2000, p. 7-16.

Research output: Contribution to journalArticle

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