Cognition and behavior after temporal lobectomy in pediatric patients with intractable epilepsy

Jane Williams, May L. Griebel, Gregory B. Sharp, Frederick Boop

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

The increased use of surgical intervention for intractable epilepsy during childhood has resulted in a critical need for information concerning possible cognitive and behavioral changes in pediatric patients after surgery. In this pilot study, comprehensive neuropsychologic evaluations were completed on nine children who had a temporal lobectomy for intractable epilepsy before 16 years of age. Performances before and after surgery were compared using cognitive and behavioral measures. Repeated measures analysis of variance did not indicate differences in performance on the basis of laterality of surgery, although the number of left (n = 5) vs right (n = 4) temporal resections was small. Paired comparison t tests, which included all patients, did not suggest marked changes in cognitive functioning after surgery, although decreases in delayed verbal memory were evident. Positive effects on quality of life during the first year after surgical intervention were suggested by reduced internalizing symptoms and increased social interaction. Replication of this study is recommended with a larger number of patients and multicenter collaboration.

Original languageEnglish (US)
Pages (from-to)189-194
Number of pages6
JournalPediatric Neurology
Volume19
Issue number3
DOIs
StatePublished - Sep 1 1998
Externally publishedYes

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Cognition
Pediatrics
Repression (Psychology)
Matched-Pair Analysis
Interpersonal Relations
Analysis of Variance
Quality of Life
Drug Resistant Epilepsy

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

Cite this

Cognition and behavior after temporal lobectomy in pediatric patients with intractable epilepsy. / Williams, Jane; Griebel, May L.; Sharp, Gregory B.; Boop, Frederick.

In: Pediatric Neurology, Vol. 19, No. 3, 01.09.1998, p. 189-194.

Research output: Contribution to journalArticle

Williams, Jane ; Griebel, May L. ; Sharp, Gregory B. ; Boop, Frederick. / Cognition and behavior after temporal lobectomy in pediatric patients with intractable epilepsy. In: Pediatric Neurology. 1998 ; Vol. 19, No. 3. pp. 189-194.
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