Collagen polymorphism in lung fibrosis

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Lung connective tissue plays a critical role in the architectural integrity and function of the lung. Therefore, a detailed knowledge of the chemical nature of the extracellular matrix elements in normal lung and their possible alterations in disease states is essential to understanding the pathogenetic mechanisms. As is true for all connective tissues, lung connective tissue is composed of collagen, elastin and proteoglycans. Of these, collagen is the most abundant protein, comprising approximately 11% of normal adult lung. It has the greatest tensile strength and probably is intimately involved in the mechanical properties of the lung.

Original languageEnglish (US)
Pages (from-to)95-107
Number of pages13
JournalJournal of UOEH
Volume4
Issue numberSuppl.
StatePublished - Jan 1 1982

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Fibrosis
Collagen
Lung
Connective Tissue
Elastin
Tensile Strength
Proteoglycans
Extracellular Matrix
Proteins

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

Cite this

Collagen polymorphism in lung fibrosis. / Kang, Andrew; Seyer, J. M.; Postlethwaite, Arnold.

In: Journal of UOEH, Vol. 4, No. Suppl., 01.01.1982, p. 95-107.

Research output: Contribution to journalArticle

Kang, A, Seyer, JM & Postlethwaite, A 1982, 'Collagen polymorphism in lung fibrosis', Journal of UOEH, vol. 4, no. Suppl., pp. 95-107.
Kang, Andrew ; Seyer, J. M. ; Postlethwaite, Arnold. / Collagen polymorphism in lung fibrosis. In: Journal of UOEH. 1982 ; Vol. 4, No. Suppl. pp. 95-107.
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