Colon cancer, version 1.2017

Clinical practice guidelines in oncology

Al B. Benson, Alan P. Venook, Lynette Cederquist, Emily Chan, Yi Jen Chen, Harry S. Cooper, Dustin Deming, Paul F. Engstrom, Peter C. Enzinger, Alessandro Fichera, Jean L. Grem, Axel Grothey, Howard S. Hochster, Sarah Hoffe, Steven Hunt, Ahmed Kamel, Natalie Kirilcuk, Smitha Krishnamurthi, Wells A. Messersmith, Mary F. Mulcahy & 13 others James D. Murphy, Steven Nurkin, Leonard Saltz, Sunil Sharma, David Shibata, John M. Skibber, Constantinos T. Sofocleous, Elena M. Stoffel, Eden Stotsky-Himelfarb, Christopher G. Willett, Christina S. Wu, Kristina M. Gregory, Deborah Freedman-Cass

Research output: Contribution to journalReview article

159 Citations (Scopus)

Abstract

This portion of the NCCN Guidelines for Colon Cancer focuses on the use of systemic therapy in metastatic disease. Considerations for treatment selection among 32 different monotherapies and combination regimens in up to 7 lines of therapy have included treatment history, extent of disease, goals of treatment, the efficacy and toxicity profiles of the regimens, KRAS/NRAS mutational status, and patient comorbidities and preferences. Location of the primary tumor, the BRAF mutation status, and tumor microsatellite stability should also be considered in treatment decisions.

Original languageEnglish (US)
Pages (from-to)370-398
Number of pages29
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume15
Issue number3
DOIs
StatePublished - Mar 1 2017

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Practice Guidelines
Colonic Neoplasms
Patient Preference
Microsatellite Repeats
Comorbidity
Neoplasms
History
Guidelines
Mutation
Therapeutics

All Science Journal Classification (ASJC) codes

  • Oncology

Cite this

Benson, A. B., Venook, A. P., Cederquist, L., Chan, E., Chen, Y. J., Cooper, H. S., ... Freedman-Cass, D. (2017). Colon cancer, version 1.2017: Clinical practice guidelines in oncology. JNCCN Journal of the National Comprehensive Cancer Network, 15(3), 370-398. https://doi.org/10.6004/jnccn.2017.0036

Colon cancer, version 1.2017 : Clinical practice guidelines in oncology. / Benson, Al B.; Venook, Alan P.; Cederquist, Lynette; Chan, Emily; Chen, Yi Jen; Cooper, Harry S.; Deming, Dustin; Engstrom, Paul F.; Enzinger, Peter C.; Fichera, Alessandro; Grem, Jean L.; Grothey, Axel; Hochster, Howard S.; Hoffe, Sarah; Hunt, Steven; Kamel, Ahmed; Kirilcuk, Natalie; Krishnamurthi, Smitha; Messersmith, Wells A.; Mulcahy, Mary F.; Murphy, James D.; Nurkin, Steven; Saltz, Leonard; Sharma, Sunil; Shibata, David; Skibber, John M.; Sofocleous, Constantinos T.; Stoffel, Elena M.; Stotsky-Himelfarb, Eden; Willett, Christopher G.; Wu, Christina S.; Gregory, Kristina M.; Freedman-Cass, Deborah.

In: JNCCN Journal of the National Comprehensive Cancer Network, Vol. 15, No. 3, 01.03.2017, p. 370-398.

Research output: Contribution to journalReview article

Benson, AB, Venook, AP, Cederquist, L, Chan, E, Chen, YJ, Cooper, HS, Deming, D, Engstrom, PF, Enzinger, PC, Fichera, A, Grem, JL, Grothey, A, Hochster, HS, Hoffe, S, Hunt, S, Kamel, A, Kirilcuk, N, Krishnamurthi, S, Messersmith, WA, Mulcahy, MF, Murphy, JD, Nurkin, S, Saltz, L, Sharma, S, Shibata, D, Skibber, JM, Sofocleous, CT, Stoffel, EM, Stotsky-Himelfarb, E, Willett, CG, Wu, CS, Gregory, KM & Freedman-Cass, D 2017, 'Colon cancer, version 1.2017: Clinical practice guidelines in oncology', JNCCN Journal of the National Comprehensive Cancer Network, vol. 15, no. 3, pp. 370-398. https://doi.org/10.6004/jnccn.2017.0036
Benson, Al B. ; Venook, Alan P. ; Cederquist, Lynette ; Chan, Emily ; Chen, Yi Jen ; Cooper, Harry S. ; Deming, Dustin ; Engstrom, Paul F. ; Enzinger, Peter C. ; Fichera, Alessandro ; Grem, Jean L. ; Grothey, Axel ; Hochster, Howard S. ; Hoffe, Sarah ; Hunt, Steven ; Kamel, Ahmed ; Kirilcuk, Natalie ; Krishnamurthi, Smitha ; Messersmith, Wells A. ; Mulcahy, Mary F. ; Murphy, James D. ; Nurkin, Steven ; Saltz, Leonard ; Sharma, Sunil ; Shibata, David ; Skibber, John M. ; Sofocleous, Constantinos T. ; Stoffel, Elena M. ; Stotsky-Himelfarb, Eden ; Willett, Christopher G. ; Wu, Christina S. ; Gregory, Kristina M. ; Freedman-Cass, Deborah. / Colon cancer, version 1.2017 : Clinical practice guidelines in oncology. In: JNCCN Journal of the National Comprehensive Cancer Network. 2017 ; Vol. 15, No. 3. pp. 370-398.
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AU - Cooper, Harry S.

AU - Deming, Dustin

AU - Engstrom, Paul F.

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AU - Fichera, Alessandro

AU - Grem, Jean L.

AU - Grothey, Axel

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AU - Saltz, Leonard

AU - Sharma, Sunil

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AU - Sofocleous, Constantinos T.

AU - Stoffel, Elena M.

AU - Stotsky-Himelfarb, Eden

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