Combinational method for focal brain activation detection using MEG signal

Mehdi Rajabioun, Abbas Babajani-Feremi, Hamid Soltanian-Zadeh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Magnetoencephalography (MEG) is a neuroimaging technique for brain activation detection. This technique does not provide a unique solution due to ill-posedness of its inverse solution. Several methods are proposed to improve the MEG inverse solution. Minimum Norm (MN) is a simple method whose solution is distributed and biased toward the superficial sources. In addition, its solution is sensitive to the noise. Several methods are proposed to improve performance of the MN method. In this paper, we propose a method whose solution is less sensitive to the noise and spatially unbiased toward the superficial sources. Control of focal solution properties is achieved by specifying a parameter in the proposed method. Performance of the proposed method is compared to others using simulation studies consisting of single and multiple dipole sources as well as an extended source model. Proposed method has superior performance compared to non-iterative methods. Its performance is similar to the iterative methods but its computational load is lower.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2009
Subtitle of host publicationBiomedical Applications in Molecular, Structural, and Functional Imaging
Volume7262
DOIs
StatePublished - Jun 22 2009
Externally publishedYes
EventMedical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging - Lake Buena Vista, FL, United States
Duration: Feb 8 2009Feb 10 2009

Other

OtherMedical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging
CountryUnited States
CityLake Buena Vista, FL
Period2/8/092/10/09

Fingerprint

Magnetoencephalography
brain
Brain
Chemical activation
activation
norms
Neuroimaging
Noise
Iterative methods
dipoles

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Rajabioun, M., Babajani-Feremi, A., & Soltanian-Zadeh, H. (2009). Combinational method for focal brain activation detection using MEG signal. In Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging (Vol. 7262). [726220] https://doi.org/10.1117/12.813876

Combinational method for focal brain activation detection using MEG signal. / Rajabioun, Mehdi; Babajani-Feremi, Abbas; Soltanian-Zadeh, Hamid.

Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging. Vol. 7262 2009. 726220.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Rajabioun, M, Babajani-Feremi, A & Soltanian-Zadeh, H 2009, Combinational method for focal brain activation detection using MEG signal. in Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging. vol. 7262, 726220, Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging, Lake Buena Vista, FL, United States, 2/8/09. https://doi.org/10.1117/12.813876
Rajabioun M, Babajani-Feremi A, Soltanian-Zadeh H. Combinational method for focal brain activation detection using MEG signal. In Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging. Vol. 7262. 2009. 726220 https://doi.org/10.1117/12.813876
Rajabioun, Mehdi ; Babajani-Feremi, Abbas ; Soltanian-Zadeh, Hamid. / Combinational method for focal brain activation detection using MEG signal. Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging. Vol. 7262 2009.
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