Common carotid artery intima-media thickness in patients with brain infarction and intracerebral haemorrhage

Konstantinos N. Vemmos, Georgios Tsivgoulis, Konstantinos Spengos, Christos M. Papamichael, Nikolaos Zakopoulos, Michael Daffertshofer, John P. Lekakis, Myron Mavrikakis

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

An increase in the intima-media thickness of the common carotid artery (CCA-IMT) is generally considered as an early marker of atherosclerosis and has been associated with a higher risk of stroke and myocardial infarction. There is no evidence of an association between the IMT and cerebral bleeding. We investigated cross-sectionally the diagnostic ability of vascular risk factors, including CCA-IMT, to distinguish between brain infarction (BI) and intracerebral haemorrhage (ICH). Patients suffering from BI (n = 126) had significantly (p < 0.05) higher CCA-IMT when compared to the ICH population (n = 30). The multinomial logistic regression procedure selected CCA-IMT as an independent factor able to discriminate between BI and ICH. The risk of BI versus ICH increased continuously with increasing CCA-IMT. After adjustment for cardiovascular risk factors the odds ratio for BI per 0.1 mm CCA-IMT increase was 1.29 (95% CI: 1.03-1.61). The present results demonstrate the possible predictive power of non-invasive measurement of the CCA-IMT with respect to BI versus ICH and deserve further investigation.

Original languageEnglish (US)
Pages (from-to)280-286
Number of pages7
JournalCerebrovascular Diseases
Volume17
Issue number4
DOIs
StatePublished - May 26 2004
Externally publishedYes

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Brain Infarction
Carotid Intima-Media Thickness
Intracranial Hemorrhages
Common Carotid Artery
Cerebral Hemorrhage
Atherosclerosis
Logistic Models
Stroke
Odds Ratio
Myocardial Infarction
Hemorrhage
Population

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Vemmos, K. N., Tsivgoulis, G., Spengos, K., Papamichael, C. M., Zakopoulos, N., Daffertshofer, M., ... Mavrikakis, M. (2004). Common carotid artery intima-media thickness in patients with brain infarction and intracerebral haemorrhage. Cerebrovascular Diseases, 17(4), 280-286. https://doi.org/10.1159/000077338

Common carotid artery intima-media thickness in patients with brain infarction and intracerebral haemorrhage. / Vemmos, Konstantinos N.; Tsivgoulis, Georgios; Spengos, Konstantinos; Papamichael, Christos M.; Zakopoulos, Nikolaos; Daffertshofer, Michael; Lekakis, John P.; Mavrikakis, Myron.

In: Cerebrovascular Diseases, Vol. 17, No. 4, 26.05.2004, p. 280-286.

Research output: Contribution to journalArticle

Vemmos, KN, Tsivgoulis, G, Spengos, K, Papamichael, CM, Zakopoulos, N, Daffertshofer, M, Lekakis, JP & Mavrikakis, M 2004, 'Common carotid artery intima-media thickness in patients with brain infarction and intracerebral haemorrhage', Cerebrovascular Diseases, vol. 17, no. 4, pp. 280-286. https://doi.org/10.1159/000077338
Vemmos, Konstantinos N. ; Tsivgoulis, Georgios ; Spengos, Konstantinos ; Papamichael, Christos M. ; Zakopoulos, Nikolaos ; Daffertshofer, Michael ; Lekakis, John P. ; Mavrikakis, Myron. / Common carotid artery intima-media thickness in patients with brain infarction and intracerebral haemorrhage. In: Cerebrovascular Diseases. 2004 ; Vol. 17, No. 4. pp. 280-286.
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