Comparison of brain network models using cross-frequency coupling and attack strategies

Marios Antonakakis, Stavros I. Dimitriadis, Michalis Zervakis, Roozbeh Rezaie, Abbas Babajani-Feremi, Sifis Micheloyannis, George Zouridakis, Andrew Papanicolaou

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Abstract

Several neuroimaging studies have suggested that functional brain connectivity networks exhibit 'small-world' characteristics, whereas recent studies based on structural data have proposed a 'rich-club' organization of brain networks, whereby hubs of high connection density tend to connect among themselves compared to nodes of lower density. In this study, we adopted an 'attack strategy' to compare the rich-club and small-world organizations and identify the model that describes best the topology of brain connectivity. We hypothesized that the highest reduction in global efficiency caused by a targeted attack on each model's hubs would reveal the organization that better describes the topology of the underlying brain networks. We applied this approach to magnetoencephalographic data obtained at rest from neurologically intact controls and mild traumatic brain injury patients. Functional connectivity networks were computed using phase-to-amplitude cross-frequency coupling between the δ and β frequency bands. Our results suggest that resting state MEG connectivity networks follow a rich-club organization.

Original languageEnglish (US)
Title of host publication2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages7426-7429
Number of pages4
ISBN (Electronic)9781424492718
DOIs
StatePublished - Nov 4 2015
Event37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy
Duration: Aug 25 2015Aug 29 2015

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2015-November
ISSN (Print)1557-170X

Other

Other37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
CountryItaly
CityMilan
Period8/25/158/29/15

Fingerprint

Brain
Brain Concussion
Topology
Small-world networks
Neuroimaging
Frequency bands

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Antonakakis, M., Dimitriadis, S. I., Zervakis, M., Rezaie, R., Babajani-Feremi, A., Micheloyannis, S., ... Papanicolaou, A. (2015). Comparison of brain network models using cross-frequency coupling and attack strategies. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 (pp. 7426-7429). [7320108] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2015-November). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7320108

Comparison of brain network models using cross-frequency coupling and attack strategies. / Antonakakis, Marios; Dimitriadis, Stavros I.; Zervakis, Michalis; Rezaie, Roozbeh; Babajani-Feremi, Abbas; Micheloyannis, Sifis; Zouridakis, George; Papanicolaou, Andrew.

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. p. 7426-7429 7320108 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2015-November).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Antonakakis, M, Dimitriadis, SI, Zervakis, M, Rezaie, R, Babajani-Feremi, A, Micheloyannis, S, Zouridakis, G & Papanicolaou, A 2015, Comparison of brain network models using cross-frequency coupling and attack strategies. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015., 7320108, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, vol. 2015-November, Institute of Electrical and Electronics Engineers Inc., pp. 7426-7429, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 8/25/15. https://doi.org/10.1109/EMBC.2015.7320108
Antonakakis M, Dimitriadis SI, Zervakis M, Rezaie R, Babajani-Feremi A, Micheloyannis S et al. Comparison of brain network models using cross-frequency coupling and attack strategies. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc. 2015. p. 7426-7429. 7320108. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2015.7320108
Antonakakis, Marios ; Dimitriadis, Stavros I. ; Zervakis, Michalis ; Rezaie, Roozbeh ; Babajani-Feremi, Abbas ; Micheloyannis, Sifis ; Zouridakis, George ; Papanicolaou, Andrew. / Comparison of brain network models using cross-frequency coupling and attack strategies. 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 7426-7429 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).
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