Comparison of metabolic rates, language, and memory in subcortical aphasias

E. Metter, Walter H. Riege, Wayne R. Hanson, David E. Kuhl, Michael E. Phelps, Larry R. Squire, Claude G. Wasterlain, D. Frank Benson

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

Four patients with subcortical lesions and either aphasia or amnesia were compared to four patients with cortical lesions and aphasia. Each patient had [18F] fluorodeoxyglucose positron-emission computed tomography, language, and memory evaluationś. Marked metabolic depression was found in the thalamus and caudate in all patients. The subcortical patients had only mild left-cortical changes, while the cortical patients showed marked cortical metabolic changes in the left hemisphere. Language changes were mild in the subcortical patients, while moderate to severe in the cortical patients. All patients showed severe verbal memory dysfunction. The only common abnormalities in the two groups were metabolic changes in the thalamus and severity of verbal memory dysfunction. These findings suggest a relationship between verbal memory and thalamic function.

Original languageEnglish (US)
Pages (from-to)33-47
Number of pages15
JournalBrain and Language
Volume19
Issue number1
DOIs
StatePublished - Jan 1 1983

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Aphasia
speech disorder
Language
language
language change
Thalamus
Emission-Computed Tomography
Amnesia
evaluation
Fluorodeoxyglucose F18
Positron-Emission Tomography
Group

All Science Journal Classification (ASJC) codes

  • Experimental and Cognitive Psychology
  • Language and Linguistics
  • Linguistics and Language
  • Cognitive Neuroscience
  • Speech and Hearing

Cite this

Metter, E., Riege, W. H., Hanson, W. R., Kuhl, D. E., Phelps, M. E., Squire, L. R., ... Benson, D. F. (1983). Comparison of metabolic rates, language, and memory in subcortical aphasias. Brain and Language, 19(1), 33-47. https://doi.org/10.1016/0093-934X(83)90054-8

Comparison of metabolic rates, language, and memory in subcortical aphasias. / Metter, E.; Riege, Walter H.; Hanson, Wayne R.; Kuhl, David E.; Phelps, Michael E.; Squire, Larry R.; Wasterlain, Claude G.; Benson, D. Frank.

In: Brain and Language, Vol. 19, No. 1, 01.01.1983, p. 33-47.

Research output: Contribution to journalArticle

Metter, E, Riege, WH, Hanson, WR, Kuhl, DE, Phelps, ME, Squire, LR, Wasterlain, CG & Benson, DF 1983, 'Comparison of metabolic rates, language, and memory in subcortical aphasias', Brain and Language, vol. 19, no. 1, pp. 33-47. https://doi.org/10.1016/0093-934X(83)90054-8
Metter, E. ; Riege, Walter H. ; Hanson, Wayne R. ; Kuhl, David E. ; Phelps, Michael E. ; Squire, Larry R. ; Wasterlain, Claude G. ; Benson, D. Frank. / Comparison of metabolic rates, language, and memory in subcortical aphasias. In: Brain and Language. 1983 ; Vol. 19, No. 1. pp. 33-47.
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