Comprehensive surgical staging for endometrial cancer in obese patients

David E. Cohn, Leigh G. Seamon, Shannon A. Bryant, Patrick S. Rheaume, Kristopher Kimball, Warner K. Huh, Jeffrey M. Fowler, Gary S. Phillips

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

OBJECTIVE: To compare adequacy and outcomes of surgical staging for endometrial cancer in obese women by robotics or laparotomy. METHODS: Clinical stage I or occult stage II endometrial cancer patients with body mass indexes (BMIs) of at least 30 (BMI is calculated as weight (kg)/[height (m)] 2) were identified undergoing robotic staging and matched 1:2 with laparotomy patients. Patient characteristics, operative times, complications, and pathologic factors were collected. An adequate lymphadenectomy was defined arbitrarily as at least 10 total nodes removed, and adequate pelvic and paraaortic lymphadenectomy was defined as at least six and at least four nodes removed, respectively. RESULTS: A total of 109 patients underwent surgery with the intent of robotic staging and were matched to 191 laparotomy patients. The mean BMI was 40 for each group. The robotic conversion rate was 15.6% (95% confidence interval [CI] 9.5-24.2%). Ninety-two completed robotic patients were compared with 162 matched laparotomy patients. The two groups were comparable regarding total lymph node count (25±13 compared with 24±12, P=.45) and the percentage of patients undergoing adequate lymphadenectomy (85% compared with 91%, P=.16) and adequate pelvic (90% compared with 95%, P=.16) and aortic lymphadenectomy (76% compared with 79%, P=.70) for robotic and laparotomy patients, respectively, but there was limited power to detect this difference. The blood transfusion rate (2% compared with 9%, odds ratio [OR] 0.22, 95% CI 0.05-0.97, P=.046), the number of nights in the hospital (1 compared with 3, P<.001), complications (11% compared with 27%, OR 0.29, 95% CI 0.13-0.65 P=.003), and wound problems (2% compared with 17%, OR 0.10, 95% CI 0.02-0.43, P=.002) were reduced for robotic surgery.CONCLUSION: In obese women with endometrial cancer, robotic comprehensive surgical staging is feasible. Importantly, obesity may not compromise the ability to adequately stage patients robotically.

Original languageEnglish (US)
Pages (from-to)16-21
Number of pages6
JournalObstetrics and gynecology
Volume114
Issue number1
DOIs
StatePublished - Jul 1 2009

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Endometrial Neoplasms
Robotics
Laparotomy
Lymph Node Excision
Confidence Intervals
Body Mass Index
Odds Ratio
Operative Time
Blood Transfusion
Obesity
Lymph Nodes
Weights and Measures
Wounds and Injuries

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

Cohn, D. E., Seamon, L. G., Bryant, S. A., Rheaume, P. S., Kimball, K., Huh, W. K., ... Phillips, G. S. (2009). Comprehensive surgical staging for endometrial cancer in obese patients. Obstetrics and gynecology, 114(1), 16-21. https://doi.org/10.1097/AOG.0b013e3181aa96c7

Comprehensive surgical staging for endometrial cancer in obese patients. / Cohn, David E.; Seamon, Leigh G.; Bryant, Shannon A.; Rheaume, Patrick S.; Kimball, Kristopher; Huh, Warner K.; Fowler, Jeffrey M.; Phillips, Gary S.

In: Obstetrics and gynecology, Vol. 114, No. 1, 01.07.2009, p. 16-21.

Research output: Contribution to journalArticle

Cohn, DE, Seamon, LG, Bryant, SA, Rheaume, PS, Kimball, K, Huh, WK, Fowler, JM & Phillips, GS 2009, 'Comprehensive surgical staging for endometrial cancer in obese patients', Obstetrics and gynecology, vol. 114, no. 1, pp. 16-21. https://doi.org/10.1097/AOG.0b013e3181aa96c7
Cohn, David E. ; Seamon, Leigh G. ; Bryant, Shannon A. ; Rheaume, Patrick S. ; Kimball, Kristopher ; Huh, Warner K. ; Fowler, Jeffrey M. ; Phillips, Gary S. / Comprehensive surgical staging for endometrial cancer in obese patients. In: Obstetrics and gynecology. 2009 ; Vol. 114, No. 1. pp. 16-21.
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AU - Seamon, Leigh G.

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AU - Rheaume, Patrick S.

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AU - Huh, Warner K.

AU - Fowler, Jeffrey M.

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N2 - OBJECTIVE: To compare adequacy and outcomes of surgical staging for endometrial cancer in obese women by robotics or laparotomy. METHODS: Clinical stage I or occult stage II endometrial cancer patients with body mass indexes (BMIs) of at least 30 (BMI is calculated as weight (kg)/[height (m)] 2) were identified undergoing robotic staging and matched 1:2 with laparotomy patients. Patient characteristics, operative times, complications, and pathologic factors were collected. An adequate lymphadenectomy was defined arbitrarily as at least 10 total nodes removed, and adequate pelvic and paraaortic lymphadenectomy was defined as at least six and at least four nodes removed, respectively. RESULTS: A total of 109 patients underwent surgery with the intent of robotic staging and were matched to 191 laparotomy patients. The mean BMI was 40 for each group. The robotic conversion rate was 15.6% (95% confidence interval [CI] 9.5-24.2%). Ninety-two completed robotic patients were compared with 162 matched laparotomy patients. The two groups were comparable regarding total lymph node count (25±13 compared with 24±12, P=.45) and the percentage of patients undergoing adequate lymphadenectomy (85% compared with 91%, P=.16) and adequate pelvic (90% compared with 95%, P=.16) and aortic lymphadenectomy (76% compared with 79%, P=.70) for robotic and laparotomy patients, respectively, but there was limited power to detect this difference. The blood transfusion rate (2% compared with 9%, odds ratio [OR] 0.22, 95% CI 0.05-0.97, P=.046), the number of nights in the hospital (1 compared with 3, P<.001), complications (11% compared with 27%, OR 0.29, 95% CI 0.13-0.65 P=.003), and wound problems (2% compared with 17%, OR 0.10, 95% CI 0.02-0.43, P=.002) were reduced for robotic surgery.CONCLUSION: In obese women with endometrial cancer, robotic comprehensive surgical staging is feasible. Importantly, obesity may not compromise the ability to adequately stage patients robotically.

AB - OBJECTIVE: To compare adequacy and outcomes of surgical staging for endometrial cancer in obese women by robotics or laparotomy. METHODS: Clinical stage I or occult stage II endometrial cancer patients with body mass indexes (BMIs) of at least 30 (BMI is calculated as weight (kg)/[height (m)] 2) were identified undergoing robotic staging and matched 1:2 with laparotomy patients. Patient characteristics, operative times, complications, and pathologic factors were collected. An adequate lymphadenectomy was defined arbitrarily as at least 10 total nodes removed, and adequate pelvic and paraaortic lymphadenectomy was defined as at least six and at least four nodes removed, respectively. RESULTS: A total of 109 patients underwent surgery with the intent of robotic staging and were matched to 191 laparotomy patients. The mean BMI was 40 for each group. The robotic conversion rate was 15.6% (95% confidence interval [CI] 9.5-24.2%). Ninety-two completed robotic patients were compared with 162 matched laparotomy patients. The two groups were comparable regarding total lymph node count (25±13 compared with 24±12, P=.45) and the percentage of patients undergoing adequate lymphadenectomy (85% compared with 91%, P=.16) and adequate pelvic (90% compared with 95%, P=.16) and aortic lymphadenectomy (76% compared with 79%, P=.70) for robotic and laparotomy patients, respectively, but there was limited power to detect this difference. The blood transfusion rate (2% compared with 9%, odds ratio [OR] 0.22, 95% CI 0.05-0.97, P=.046), the number of nights in the hospital (1 compared with 3, P<.001), complications (11% compared with 27%, OR 0.29, 95% CI 0.13-0.65 P=.003), and wound problems (2% compared with 17%, OR 0.10, 95% CI 0.02-0.43, P=.002) were reduced for robotic surgery.CONCLUSION: In obese women with endometrial cancer, robotic comprehensive surgical staging is feasible. Importantly, obesity may not compromise the ability to adequately stage patients robotically.

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