Correlation between blood pressure responses to dietary sodium and potassium intervention in a Chinese population

Qi Zhao, Dongfeng Gu, Jing Chen, Lydia A. Bazzano, Dabeeru C. Rao, James E. Hixson, Cashell E. Jaquish, Jie Cao, Jichun Chen, Jianxin Li, Treva Rice, Jiang He

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background Blood pressure (BP) responses to dietary sodium and potassium intake vary among individuals. We examined the correlation between BP responses to dietary low-sodium, high-sodium, and potassium supplementation interventions in a feeding study.MethodsA total of 1,906 Chinese aged 16 years participated in the dietary intervention that included a 7-day low-salt intervention (51.3 mmol/day), a 7-day high-salt intervention (307.8 mmol/day), and a 7-day high-salt plus potassium supplementation (60 mmol/day) intervention. BP was measured nine times during the 3-day baseline observation and during the last 3 days of each intervention phase using a random-zero sphygmomanometer.ResultsThe correlation coefficients (95% confidence intervals (CIs)) of the BP responses to low-sodium and high-sodium interventions were 0.47 (0.51 to 0.44), 0.47 (0.50 to 0.43), and 0.45 (0.49 to 0.42) for systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP), respectively (all P 0.0001). The correlation coefficients (95% CI) of the BP responses to high-sodium intervention and potassium supplementation were 0.52 (0.56 to 0.49), 0.48 (0.52 to 0.45), and 0.52 (0.55 to 0.48) for SBP, DBP, and MAP, respectively (all P 0.0001). The coefficients were moderate, varying from 0.28 to 0.34, between BP responses to low-sodium and high-sodium interventions (all P 0.0001).ConclusionsThese results indicate there is a moderate correlation between BP responses to low-sodium and to high-sodium interventions, and BP responses to high-sodium intervention and potassium supplementation. Furthermore, our study suggests that individuals who were more sensitive to high-sodium diet might benefit more from a low-sodium and/or high-potassium intervention aimed at lowering BP levels.

Original languageEnglish (US)
Pages (from-to)1281-1286
Number of pages6
JournalAmerican Journal of Hypertension
Volume22
Issue number12
DOIs
StatePublished - Dec 1 2009
Externally publishedYes

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Dietary Potassium
Dietary Sodium
Blood Pressure
Sodium
Population
Potassium
Salts
Arterial Pressure
Confidence Intervals
Sphygmomanometers

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Correlation between blood pressure responses to dietary sodium and potassium intervention in a Chinese population. / Zhao, Qi; Gu, Dongfeng; Chen, Jing; Bazzano, Lydia A.; Rao, Dabeeru C.; Hixson, James E.; Jaquish, Cashell E.; Cao, Jie; Chen, Jichun; Li, Jianxin; Rice, Treva; He, Jiang.

In: American Journal of Hypertension, Vol. 22, No. 12, 01.12.2009, p. 1281-1286.

Research output: Contribution to journalArticle

Zhao, Q, Gu, D, Chen, J, Bazzano, LA, Rao, DC, Hixson, JE, Jaquish, CE, Cao, J, Chen, J, Li, J, Rice, T & He, J 2009, 'Correlation between blood pressure responses to dietary sodium and potassium intervention in a Chinese population', American Journal of Hypertension, vol. 22, no. 12, pp. 1281-1286. https://doi.org/10.1038/ajh.2009.176
Zhao, Qi ; Gu, Dongfeng ; Chen, Jing ; Bazzano, Lydia A. ; Rao, Dabeeru C. ; Hixson, James E. ; Jaquish, Cashell E. ; Cao, Jie ; Chen, Jichun ; Li, Jianxin ; Rice, Treva ; He, Jiang. / Correlation between blood pressure responses to dietary sodium and potassium intervention in a Chinese population. In: American Journal of Hypertension. 2009 ; Vol. 22, No. 12. pp. 1281-1286.
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abstract = "Background Blood pressure (BP) responses to dietary sodium and potassium intake vary among individuals. We examined the correlation between BP responses to dietary low-sodium, high-sodium, and potassium supplementation interventions in a feeding study.MethodsA total of 1,906 Chinese aged 16 years participated in the dietary intervention that included a 7-day low-salt intervention (51.3 mmol/day), a 7-day high-salt intervention (307.8 mmol/day), and a 7-day high-salt plus potassium supplementation (60 mmol/day) intervention. BP was measured nine times during the 3-day baseline observation and during the last 3 days of each intervention phase using a random-zero sphygmomanometer.ResultsThe correlation coefficients (95{\%} confidence intervals (CIs)) of the BP responses to low-sodium and high-sodium interventions were 0.47 (0.51 to 0.44), 0.47 (0.50 to 0.43), and 0.45 (0.49 to 0.42) for systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP), respectively (all P 0.0001). The correlation coefficients (95{\%} CI) of the BP responses to high-sodium intervention and potassium supplementation were 0.52 (0.56 to 0.49), 0.48 (0.52 to 0.45), and 0.52 (0.55 to 0.48) for SBP, DBP, and MAP, respectively (all P 0.0001). The coefficients were moderate, varying from 0.28 to 0.34, between BP responses to low-sodium and high-sodium interventions (all P 0.0001).ConclusionsThese results indicate there is a moderate correlation between BP responses to low-sodium and to high-sodium interventions, and BP responses to high-sodium intervention and potassium supplementation. Furthermore, our study suggests that individuals who were more sensitive to high-sodium diet might benefit more from a low-sodium and/or high-potassium intervention aimed at lowering BP levels.",
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T1 - Correlation between blood pressure responses to dietary sodium and potassium intervention in a Chinese population

AU - Zhao, Qi

AU - Gu, Dongfeng

AU - Chen, Jing

AU - Bazzano, Lydia A.

AU - Rao, Dabeeru C.

AU - Hixson, James E.

AU - Jaquish, Cashell E.

AU - Cao, Jie

AU - Chen, Jichun

AU - Li, Jianxin

AU - Rice, Treva

AU - He, Jiang

PY - 2009/12/1

Y1 - 2009/12/1

N2 - Background Blood pressure (BP) responses to dietary sodium and potassium intake vary among individuals. We examined the correlation between BP responses to dietary low-sodium, high-sodium, and potassium supplementation interventions in a feeding study.MethodsA total of 1,906 Chinese aged 16 years participated in the dietary intervention that included a 7-day low-salt intervention (51.3 mmol/day), a 7-day high-salt intervention (307.8 mmol/day), and a 7-day high-salt plus potassium supplementation (60 mmol/day) intervention. BP was measured nine times during the 3-day baseline observation and during the last 3 days of each intervention phase using a random-zero sphygmomanometer.ResultsThe correlation coefficients (95% confidence intervals (CIs)) of the BP responses to low-sodium and high-sodium interventions were 0.47 (0.51 to 0.44), 0.47 (0.50 to 0.43), and 0.45 (0.49 to 0.42) for systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP), respectively (all P 0.0001). The correlation coefficients (95% CI) of the BP responses to high-sodium intervention and potassium supplementation were 0.52 (0.56 to 0.49), 0.48 (0.52 to 0.45), and 0.52 (0.55 to 0.48) for SBP, DBP, and MAP, respectively (all P 0.0001). The coefficients were moderate, varying from 0.28 to 0.34, between BP responses to low-sodium and high-sodium interventions (all P 0.0001).ConclusionsThese results indicate there is a moderate correlation between BP responses to low-sodium and to high-sodium interventions, and BP responses to high-sodium intervention and potassium supplementation. Furthermore, our study suggests that individuals who were more sensitive to high-sodium diet might benefit more from a low-sodium and/or high-potassium intervention aimed at lowering BP levels.

AB - Background Blood pressure (BP) responses to dietary sodium and potassium intake vary among individuals. We examined the correlation between BP responses to dietary low-sodium, high-sodium, and potassium supplementation interventions in a feeding study.MethodsA total of 1,906 Chinese aged 16 years participated in the dietary intervention that included a 7-day low-salt intervention (51.3 mmol/day), a 7-day high-salt intervention (307.8 mmol/day), and a 7-day high-salt plus potassium supplementation (60 mmol/day) intervention. BP was measured nine times during the 3-day baseline observation and during the last 3 days of each intervention phase using a random-zero sphygmomanometer.ResultsThe correlation coefficients (95% confidence intervals (CIs)) of the BP responses to low-sodium and high-sodium interventions were 0.47 (0.51 to 0.44), 0.47 (0.50 to 0.43), and 0.45 (0.49 to 0.42) for systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP), respectively (all P 0.0001). The correlation coefficients (95% CI) of the BP responses to high-sodium intervention and potassium supplementation were 0.52 (0.56 to 0.49), 0.48 (0.52 to 0.45), and 0.52 (0.55 to 0.48) for SBP, DBP, and MAP, respectively (all P 0.0001). The coefficients were moderate, varying from 0.28 to 0.34, between BP responses to low-sodium and high-sodium interventions (all P 0.0001).ConclusionsThese results indicate there is a moderate correlation between BP responses to low-sodium and to high-sodium interventions, and BP responses to high-sodium intervention and potassium supplementation. Furthermore, our study suggests that individuals who were more sensitive to high-sodium diet might benefit more from a low-sodium and/or high-potassium intervention aimed at lowering BP levels.

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