Correlation between long-term in vivo amalgam restorations and the presence of heavy elements in the dental pulp

Mohammad Ali Saghiri, Sepideh Banava, Mohamad Amin Sabzian, James L. Gutmann, Armen Asatourian, Golam H. Ramezani, Franklin Garcia-Godoy, Nader Sheibani

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Project: To measure the levels of heavy metals (Hg, Sn) in the dental pulp and blood samples of patients with long-term amalgam restorations. Procedure: 12 amalgam restored and 12 non-restored, sound teeth were chosen and access cavity preparation to the pulp chamber was made. The contents were transferred and dissolved in 5. mL of concentrated nitric acid followed by placement in an oven at 180. °C for tissue digestion. After cooling the tubes each digested sample was transferred to an atomic absorption system to measure the levels of heavy metals. The blood samples of five patients in each group were randomly analyzed to determine the levels of these heavy metals in the blood and if there were a correlation between these levels in blood and pulp. Data were analyzed by t-test at a P<. 0.05 level of significance. Results: No significant difference was seen between the levels of Hg and Sn in pulp tissues ( P>. 0.05); however, the blood analysis showed higher level of Hg amalgam group ( P= 0.009). The analysis between the pulp and blood samples showed positive correlations for both Hg and Sn elements in dental pulp and the blood ( P= 1.000) ( P= 0.900). Conclusions: The long-term presence of dental amalgam (at least 5 years) did not result in any remarkable changes in the levels of mercury and tin in the pulp tissue; however, there were increases in the level of mercury in the blood circulation even five years following the placement of the restoration.

Original languageEnglish (US)
Pages (from-to)200-204
Number of pages5
JournalJournal of Trace Elements in Medicine and Biology
Volume28
Issue number2
DOIs
StatePublished - Jan 1 2014

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Mercury amalgams
Dental Pulp
Restoration
Pulp
Blood
Heavy Metals
Mercury
Dental Amalgam
Tissue
Nitric Acid
Tin
Blood Circulation
Dental Pulp Cavity
Hemodynamics
Ovens
Digestion
Tooth
Acoustic waves
Cooling

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Inorganic Chemistry

Cite this

Saghiri, M. A., Banava, S., Sabzian, M. A., Gutmann, J. L., Asatourian, A., Ramezani, G. H., ... Sheibani, N. (2014). Correlation between long-term in vivo amalgam restorations and the presence of heavy elements in the dental pulp. Journal of Trace Elements in Medicine and Biology, 28(2), 200-204. https://doi.org/10.1016/j.jtemb.2014.01.008

Correlation between long-term in vivo amalgam restorations and the presence of heavy elements in the dental pulp. / Saghiri, Mohammad Ali; Banava, Sepideh; Sabzian, Mohamad Amin; Gutmann, James L.; Asatourian, Armen; Ramezani, Golam H.; Garcia-Godoy, Franklin; Sheibani, Nader.

In: Journal of Trace Elements in Medicine and Biology, Vol. 28, No. 2, 01.01.2014, p. 200-204.

Research output: Contribution to journalArticle

Saghiri, Mohammad Ali ; Banava, Sepideh ; Sabzian, Mohamad Amin ; Gutmann, James L. ; Asatourian, Armen ; Ramezani, Golam H. ; Garcia-Godoy, Franklin ; Sheibani, Nader. / Correlation between long-term in vivo amalgam restorations and the presence of heavy elements in the dental pulp. In: Journal of Trace Elements in Medicine and Biology. 2014 ; Vol. 28, No. 2. pp. 200-204.
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