Correlation of near infrared reflectometry with intracranial pressure during intact and loss of vascular tone

Jin Zhang, Erich Wolfe, Henrietta Bada, Charles Leffler, Michael L. Daley

Research output: Contribution to journalArticle

Abstract

A near infrared reflectometer was fabricated with a laser (820 nm) diode and a photodiode detector circuit. Because the isosbestic point of HbO2 and Hb is approximately 810 nm, change in the reflected near infrared signal is approximately proportional to change of blood volume. With this instrument, recordings of local change of cerebral blood volume were obtained lateral to and along the sagittal sinus of piglets. Intracranial pressure was also recorded. A correlation analysis was employed to evaluate the strength of similarity between change in cerebral blood volume and change in intracranial pressure. During normal vascular tone, local changes of cerebral blood volume were found to have a high correlation with intracranial pressure. During loss of vascular tone, the two signals were found to be uncorrelated.

Original languageEnglish (US)
Pages (from-to)1750-1751
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume4
StatePublished - 1996
Externally publishedYes

Fingerprint

Intracranial Pressure
Blood Vessels
Blood
Infrared radiation
Recording instruments
Detector circuits
Blood Volume
Reflectometers
Lasers
Photodiodes
Diodes
Cerebral Blood Volume

All Science Journal Classification (ASJC) codes

  • Bioengineering

Cite this

Correlation of near infrared reflectometry with intracranial pressure during intact and loss of vascular tone. / Zhang, Jin; Wolfe, Erich; Bada, Henrietta; Leffler, Charles; Daley, Michael L.

In: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, Vol. 4, 1996, p. 1750-1751.

Research output: Contribution to journalArticle

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