Corrigendum to

“Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131](S235239641630175X)(10.1016/j.ebiom.2016.04.032)

Anuradha Illendula, Jane Gilmour, Jolanta Grembecka, Venkata Sesha Srimath Tirumala, Adam Boulton, Aravinda Kuntimaddi, Charles Schmidt, Lixin Wang, John A. Pulikkan, Hongliang Zong, Mahmut Parlak, Cem Kuscu, Anna Pickin, Yunpeng Zhou, Yan Gao, Lauren Mishra, Mazhar Adli, Lucio H. Castilla, Roger A. Rajewski, Kevin A. Janes & 3 others Monica L. Guzman, Constanze Bonifer, John H. Bushweller

Research output: Contribution to journalComment/debate

Abstract

The authors wish to point out that, in some instances of the text in Results section 3.5, the units of ps-ns and μs-ms to define timescales of residue dynamics were inadvertently switched. “Interestingly, these changes occur both in the μs-ms timescale dynamics (principally near the benzimidazole ring) as well as on the ps-ns timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” should read “Interestingly, these changes occur both in the ps-ns timescale dynamics (principally near the benzimidazole ring) as well as on the μs-ms timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” “For Arg131, we observe increased μs-ms timescale dynamics with compound binding.” should read “For Arg131, we observe increased ps-ns timescale dynamics with compound binding.” “For Asn104, we observe an increase in ps-ns timescale dynamics with compound binding.” should read “For Asn104, we observe an increase in μs-ms timescale dynamics with compound binding.” Also, the legend for Fig. 3 contains similar inadvertent unit switching. In the legend for Fig. 3D, “Residues showing increased ps-ns timescale motion are colored red and those showing increased μs-ms timescale motion are colored blue.” should read “Residues showing increased μs-ms timescale motion are colored red and those showing increased ps-ns timescale motion are colored blue.” In the legend for Fig. 3E, “Red indicates increased ps-ns timescale motion and blue indicates increased μs-ms timescale motion.” should read “Red indicates increased μs-ms timescale motion and blue indicates increased ps-ns timescale motion.” These errors do not alter the conclusions of the paper.

Original languageEnglish (US)
Number of pages1
JournalEBioMedicine
Volume25
DOIs
StatePublished - Nov 1 2017

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Transcription Factors
Molecules
Neoplasms
corrigendum
pyridine
benzimidazole

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Corrigendum to : “Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131](S235239641630175X)(10.1016/j.ebiom.2016.04.032). / Illendula, Anuradha; Gilmour, Jane; Grembecka, Jolanta; Tirumala, Venkata Sesha Srimath; Boulton, Adam; Kuntimaddi, Aravinda; Schmidt, Charles; Wang, Lixin; Pulikkan, John A.; Zong, Hongliang; Parlak, Mahmut; Kuscu, Cem; Pickin, Anna; Zhou, Yunpeng; Gao, Yan; Mishra, Lauren; Adli, Mazhar; Castilla, Lucio H.; Rajewski, Roger A.; Janes, Kevin A.; Guzman, Monica L.; Bonifer, Constanze; Bushweller, John H.

In: EBioMedicine, Vol. 25, 01.11.2017.

Research output: Contribution to journalComment/debate

Illendula, A, Gilmour, J, Grembecka, J, Tirumala, VSS, Boulton, A, Kuntimaddi, A, Schmidt, C, Wang, L, Pulikkan, JA, Zong, H, Parlak, M, Kuscu, C, Pickin, A, Zhou, Y, Gao, Y, Mishra, L, Adli, M, Castilla, LH, Rajewski, RA, Janes, KA, Guzman, ML, Bonifer, C & Bushweller, JH 2017, 'Corrigendum to: “Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131](S235239641630175X)(10.1016/j.ebiom.2016.04.032)', EBioMedicine, vol. 25. https://doi.org/10.1016/j.ebiom.2017.10.029
Illendula, Anuradha ; Gilmour, Jane ; Grembecka, Jolanta ; Tirumala, Venkata Sesha Srimath ; Boulton, Adam ; Kuntimaddi, Aravinda ; Schmidt, Charles ; Wang, Lixin ; Pulikkan, John A. ; Zong, Hongliang ; Parlak, Mahmut ; Kuscu, Cem ; Pickin, Anna ; Zhou, Yunpeng ; Gao, Yan ; Mishra, Lauren ; Adli, Mazhar ; Castilla, Lucio H. ; Rajewski, Roger A. ; Janes, Kevin A. ; Guzman, Monica L. ; Bonifer, Constanze ; Bushweller, John H. / Corrigendum to : “Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131](S235239641630175X)(10.1016/j.ebiom.2016.04.032). In: EBioMedicine. 2017 ; Vol. 25.
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title = "Corrigendum to: “Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131](S235239641630175X)(10.1016/j.ebiom.2016.04.032)",
abstract = "The authors wish to point out that, in some instances of the text in Results section 3.5, the units of ps-ns and μs-ms to define timescales of residue dynamics were inadvertently switched. “Interestingly, these changes occur both in the μs-ms timescale dynamics (principally near the benzimidazole ring) as well as on the ps-ns timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” should read “Interestingly, these changes occur both in the ps-ns timescale dynamics (principally near the benzimidazole ring) as well as on the μs-ms timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” “For Arg131, we observe increased μs-ms timescale dynamics with compound binding.” should read “For Arg131, we observe increased ps-ns timescale dynamics with compound binding.” “For Asn104, we observe an increase in ps-ns timescale dynamics with compound binding.” should read “For Asn104, we observe an increase in μs-ms timescale dynamics with compound binding.” Also, the legend for Fig. 3 contains similar inadvertent unit switching. In the legend for Fig. 3D, “Residues showing increased ps-ns timescale motion are colored red and those showing increased μs-ms timescale motion are colored blue.” should read “Residues showing increased μs-ms timescale motion are colored red and those showing increased ps-ns timescale motion are colored blue.” In the legend for Fig. 3E, “Red indicates increased ps-ns timescale motion and blue indicates increased μs-ms timescale motion.” should read “Red indicates increased μs-ms timescale motion and blue indicates increased ps-ns timescale motion.” These errors do not alter the conclusions of the paper.",
author = "Anuradha Illendula and Jane Gilmour and Jolanta Grembecka and Tirumala, {Venkata Sesha Srimath} and Adam Boulton and Aravinda Kuntimaddi and Charles Schmidt and Lixin Wang and Pulikkan, {John A.} and Hongliang Zong and Mahmut Parlak and Cem Kuscu and Anna Pickin and Yunpeng Zhou and Yan Gao and Lauren Mishra and Mazhar Adli and Castilla, {Lucio H.} and Rajewski, {Roger A.} and Janes, {Kevin A.} and Guzman, {Monica L.} and Constanze Bonifer and Bushweller, {John H.}",
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T2 - “Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131](S235239641630175X)(10.1016/j.ebiom.2016.04.032)

AU - Illendula, Anuradha

AU - Gilmour, Jane

AU - Grembecka, Jolanta

AU - Tirumala, Venkata Sesha Srimath

AU - Boulton, Adam

AU - Kuntimaddi, Aravinda

AU - Schmidt, Charles

AU - Wang, Lixin

AU - Pulikkan, John A.

AU - Zong, Hongliang

AU - Parlak, Mahmut

AU - Kuscu, Cem

AU - Pickin, Anna

AU - Zhou, Yunpeng

AU - Gao, Yan

AU - Mishra, Lauren

AU - Adli, Mazhar

AU - Castilla, Lucio H.

AU - Rajewski, Roger A.

AU - Janes, Kevin A.

AU - Guzman, Monica L.

AU - Bonifer, Constanze

AU - Bushweller, John H.

PY - 2017/11/1

Y1 - 2017/11/1

N2 - The authors wish to point out that, in some instances of the text in Results section 3.5, the units of ps-ns and μs-ms to define timescales of residue dynamics were inadvertently switched. “Interestingly, these changes occur both in the μs-ms timescale dynamics (principally near the benzimidazole ring) as well as on the ps-ns timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” should read “Interestingly, these changes occur both in the ps-ns timescale dynamics (principally near the benzimidazole ring) as well as on the μs-ms timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” “For Arg131, we observe increased μs-ms timescale dynamics with compound binding.” should read “For Arg131, we observe increased ps-ns timescale dynamics with compound binding.” “For Asn104, we observe an increase in ps-ns timescale dynamics with compound binding.” should read “For Asn104, we observe an increase in μs-ms timescale dynamics with compound binding.” Also, the legend for Fig. 3 contains similar inadvertent unit switching. In the legend for Fig. 3D, “Residues showing increased ps-ns timescale motion are colored red and those showing increased μs-ms timescale motion are colored blue.” should read “Residues showing increased μs-ms timescale motion are colored red and those showing increased ps-ns timescale motion are colored blue.” In the legend for Fig. 3E, “Red indicates increased ps-ns timescale motion and blue indicates increased μs-ms timescale motion.” should read “Red indicates increased μs-ms timescale motion and blue indicates increased ps-ns timescale motion.” These errors do not alter the conclusions of the paper.

AB - The authors wish to point out that, in some instances of the text in Results section 3.5, the units of ps-ns and μs-ms to define timescales of residue dynamics were inadvertently switched. “Interestingly, these changes occur both in the μs-ms timescale dynamics (principally near the benzimidazole ring) as well as on the ps-ns timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” should read “Interestingly, these changes occur both in the ps-ns timescale dynamics (principally near the benzimidazole ring) as well as on the μs-ms timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” “For Arg131, we observe increased μs-ms timescale dynamics with compound binding.” should read “For Arg131, we observe increased ps-ns timescale dynamics with compound binding.” “For Asn104, we observe an increase in ps-ns timescale dynamics with compound binding.” should read “For Asn104, we observe an increase in μs-ms timescale dynamics with compound binding.” Also, the legend for Fig. 3 contains similar inadvertent unit switching. In the legend for Fig. 3D, “Residues showing increased ps-ns timescale motion are colored red and those showing increased μs-ms timescale motion are colored blue.” should read “Residues showing increased μs-ms timescale motion are colored red and those showing increased ps-ns timescale motion are colored blue.” In the legend for Fig. 3E, “Red indicates increased ps-ns timescale motion and blue indicates increased μs-ms timescale motion.” should read “Red indicates increased μs-ms timescale motion and blue indicates increased ps-ns timescale motion.” These errors do not alter the conclusions of the paper.

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