Creatinine clearance estimation in protein-malnourished patient

E. G. Boyce, Roland Dickerson, G. F. Cooney, G. A. Gibson, J. L. Mullen

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The study reported here was designed to compare the accuracy of several methods for estimating creatinine clearance in patients with protein malnutrition. Actual, ideal, and the lesser of actual and ideal body weights were compared for those equations in which body weight is a factor. The best predictive method was then used to determine which patient factors were associated with prediction errors. The method of Cockcroft and Gault used with the lower of ideal and actual body weights was the most precise and least biased method tested in 43 clinically stable, force-fed, protein-malnourished patients. Although selected methods of estimating creatinine clearance may be fairly accurate overall, large individual differences may limit their utility in malnourished patients.

Original languageEnglish (US)
Pages (from-to)721-726
Number of pages6
JournalClinical Pharmacy
Volume8
Issue number10
StatePublished - Jan 1 1989
Externally publishedYes

Fingerprint

Creatinine
Ideal Body Weight
Proteins
Individuality
Malnutrition
Body Weight

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

Boyce, E. G., Dickerson, R., Cooney, G. F., Gibson, G. A., & Mullen, J. L. (1989). Creatinine clearance estimation in protein-malnourished patient. Clinical Pharmacy, 8(10), 721-726.

Creatinine clearance estimation in protein-malnourished patient. / Boyce, E. G.; Dickerson, Roland; Cooney, G. F.; Gibson, G. A.; Mullen, J. L.

In: Clinical Pharmacy, Vol. 8, No. 10, 01.01.1989, p. 721-726.

Research output: Contribution to journalArticle

Boyce, EG, Dickerson, R, Cooney, GF, Gibson, GA & Mullen, JL 1989, 'Creatinine clearance estimation in protein-malnourished patient', Clinical Pharmacy, vol. 8, no. 10, pp. 721-726.
Boyce EG, Dickerson R, Cooney GF, Gibson GA, Mullen JL. Creatinine clearance estimation in protein-malnourished patient. Clinical Pharmacy. 1989 Jan 1;8(10):721-726.
Boyce, E. G. ; Dickerson, Roland ; Cooney, G. F. ; Gibson, G. A. ; Mullen, J. L. / Creatinine clearance estimation in protein-malnourished patient. In: Clinical Pharmacy. 1989 ; Vol. 8, No. 10. pp. 721-726.
@article{e23d8830a3944e0b997e1c844b7e1bc2,
title = "Creatinine clearance estimation in protein-malnourished patient",
abstract = "The study reported here was designed to compare the accuracy of several methods for estimating creatinine clearance in patients with protein malnutrition. Actual, ideal, and the lesser of actual and ideal body weights were compared for those equations in which body weight is a factor. The best predictive method was then used to determine which patient factors were associated with prediction errors. The method of Cockcroft and Gault used with the lower of ideal and actual body weights was the most precise and least biased method tested in 43 clinically stable, force-fed, protein-malnourished patients. Although selected methods of estimating creatinine clearance may be fairly accurate overall, large individual differences may limit their utility in malnourished patients.",
author = "Boyce, {E. G.} and Roland Dickerson and Cooney, {G. F.} and Gibson, {G. A.} and Mullen, {J. L.}",
year = "1989",
month = "1",
day = "1",
language = "English (US)",
volume = "8",
pages = "721--726",
journal = "Clinical Pharmacy",
issn = "0278-2677",
publisher = "American Society of Hospital Pharmacists",
number = "10",

}

TY - JOUR

T1 - Creatinine clearance estimation in protein-malnourished patient

AU - Boyce, E. G.

AU - Dickerson, Roland

AU - Cooney, G. F.

AU - Gibson, G. A.

AU - Mullen, J. L.

PY - 1989/1/1

Y1 - 1989/1/1

N2 - The study reported here was designed to compare the accuracy of several methods for estimating creatinine clearance in patients with protein malnutrition. Actual, ideal, and the lesser of actual and ideal body weights were compared for those equations in which body weight is a factor. The best predictive method was then used to determine which patient factors were associated with prediction errors. The method of Cockcroft and Gault used with the lower of ideal and actual body weights was the most precise and least biased method tested in 43 clinically stable, force-fed, protein-malnourished patients. Although selected methods of estimating creatinine clearance may be fairly accurate overall, large individual differences may limit their utility in malnourished patients.

AB - The study reported here was designed to compare the accuracy of several methods for estimating creatinine clearance in patients with protein malnutrition. Actual, ideal, and the lesser of actual and ideal body weights were compared for those equations in which body weight is a factor. The best predictive method was then used to determine which patient factors were associated with prediction errors. The method of Cockcroft and Gault used with the lower of ideal and actual body weights was the most precise and least biased method tested in 43 clinically stable, force-fed, protein-malnourished patients. Although selected methods of estimating creatinine clearance may be fairly accurate overall, large individual differences may limit their utility in malnourished patients.

UR - http://www.scopus.com/inward/record.url?scp=0024442991&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024442991&partnerID=8YFLogxK

M3 - Article

VL - 8

SP - 721

EP - 726

JO - Clinical Pharmacy

JF - Clinical Pharmacy

SN - 0278-2677

IS - 10

ER -