Cryptogenic gelastic epilepsy originating from the right temporallobe

Yaohui Chai, Bola Adamolekun

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective: To present a case of intractable cryptogenic gelastic epilepsy with ictal video-EEG to localize the seizure focus. Clinical Presentation and Intervention: A 39-year-old female presented with a 2-year history of intractable gelastic epilepsy characterized by recurrent episodes of stereotyped pathological laughter, transient unresponsiveness, automatisms and brief postictal confusion. The patient failed to respond to multiple antiepileptic drugs. Several interictal EEGs did not show any abnormalities. Magnetic resonance imaging of the head with seizure protocol and diffusion tensor imaging were normal. Ictal video-EEG monitoring showed rhythmic, sharp activity emanating from the right temporal lobe. Conclusion: This case suggests that the right temporal lobe may be actively involved in the epileptogenic network generating gelastic epilepsy. Video-EEG monitoring should be considered for patients with gelastic epilepsies to better clarify the nature of events, localize the seizure focus and correlate EEG changes with the clinical manifestations.

Original languageEnglish (US)
Pages (from-to)153-158
Number of pages6
JournalMedical Principles and Practice
Volume19
Issue number2
DOIs
StatePublished - Feb 2010

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Partial Epilepsy
Electroencephalography
Epilepsy
Seizures
Temporal Lobe
Stroke
Laughter
Automatism
Confusion
Diffusion Tensor Imaging
Anticonvulsants
Head
Magnetic Resonance Imaging

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Cryptogenic gelastic epilepsy originating from the right temporallobe. / Chai, Yaohui; Adamolekun, Bola.

In: Medical Principles and Practice, Vol. 19, No. 2, 02.2010, p. 153-158.

Research output: Contribution to journalArticle

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