Culture-negative surgical site infections

Mark Rasnake, David P. Dooley

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

Background: The appearance of postoperative surgical site infection (SSI) in the absence of culturable bacterial pathogens is a common dilemma for the surgeon. Methods: The literature was searched through references to primary articles, as well as a MEDLINE review, for reports of culture-negative SSIs. Results: Potential causes of culture-negative SSIs include prior antimicrobial therapy; the presence of fastidious or slow-growing microorganisms such as mycobacteria, Mycoplasma spp., and Legionella spp.; infection caused by mundane bacteria that may be dismissed as "contaminants"; factitious infection; and others. Conclusions: We review the recognized causes of "culture negative" SSIs and discuss the laboratory capabilities that may enhance recognition of many of these pathogens and management options.

Original languageEnglish (US)
Pages (from-to)555-565
Number of pages11
JournalSurgical Infections
Volume7
Issue number6
DOIs
StatePublished - Dec 1 2006
Externally publishedYes

Fingerprint

Surgical Wound Infection
Legionella
Mycoplasma
Mycobacterium
Infection
MEDLINE
Bacteria
Therapeutics
Surgeons

All Science Journal Classification (ASJC) codes

  • Surgery
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Culture-negative surgical site infections. / Rasnake, Mark; Dooley, David P.

In: Surgical Infections, Vol. 7, No. 6, 01.12.2006, p. 555-565.

Research output: Contribution to journalReview article

Rasnake, Mark ; Dooley, David P. / Culture-negative surgical site infections. In: Surgical Infections. 2006 ; Vol. 7, No. 6. pp. 555-565.
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