Current Expectations for Newborns Undergoing the Arterial Switch Operation

Daniel J. Dibardino, Andrew E. Allison, William K. Vaughn, E. Dean McKenzie, Charles D. Fraser, Irving L. Kron, Fred A. Crawford, Erle H. Austin, Dale W. Oller, Max Langham

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Background: The arterial switch operation (ASO) represents a remarkable success story in the surgical treatment of cyanotic congenital heart disease. This study is designed to assess recent outcomes after the ASO in babies presenting with transposition of the great arteries (TGA) and Taussig-Bing anomaly (TBA). Methods: One hundred twenty-five consecutive neonatal and infant ASOs were performed by 2 surgeons at Texas Children's Hospital between July 1, 1995 and October 1, 2003. Patients with TGA and TBA were offered ASO irrespective of patient size and associated cardiac malformations. Primary cardiac diagnoses included TGA with intact ventricular septum (TGA/IVS, n = 79, 63%), TGA with ventricular septal defect (TGA/VSD, n = 37, 30%), and Taussig Bing Anomaly (TBA, n = 9, 7%). Results: With complete follow-up, we observed a 30-day mortality rate of 1.6% (n = 2) with 2 late deaths (1.6%), for an overall actuarial survival rate of 96.3% at 7 years. Although there was a significant incidence of complex coronary ostial origin and branching including single coronary (n = 8, 6.4%) and intramural coronary artery (n = 8, 6.4%), this was not associated with increased operative risk. All patients are fully saturated and NYHA functional class I at latest clinic visit (0.3 to 88.4 months postoperatively). There have been no late coronary events. Of 121 survivors, 7 patients (5.8%) have required cardiovascular reoperation at an average of 15.3 ± 11.7 months postoperatively (range, 3.6 to 30.6 months) for an actuarial freedom from reoperation of 90% at 7 years. Conclusions: Using current methodologies, the ASO can be performed safely and with a low incidence of need for reoperation on intermediate follow-up. Recent experience indicates operative survival rates approaching 100%.

Original languageEnglish (US)
Pages (from-to)588-598
Number of pages11
JournalAnnals of surgery
Volume239
Issue number5
DOIs
StatePublished - May 1 2004
Externally publishedYes

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Transposition of Great Vessels
Double Outlet Right Ventricle
Newborn Infant
Reoperation
Survival Rate
Ventricular Septum
Ventricular Heart Septal Defects
Incidence
Ambulatory Care
Survivors
Arterial Switch Operation
Heart Diseases
Coronary Vessels
Mortality

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Dibardino, D. J., Allison, A. E., Vaughn, W. K., McKenzie, E. D., Fraser, C. D., Kron, I. L., ... Langham, M. (2004). Current Expectations for Newborns Undergoing the Arterial Switch Operation. Annals of surgery, 239(5), 588-598. https://doi.org/10.1097/01.sla.0000124293.52814.a7

Current Expectations for Newborns Undergoing the Arterial Switch Operation. / Dibardino, Daniel J.; Allison, Andrew E.; Vaughn, William K.; McKenzie, E. Dean; Fraser, Charles D.; Kron, Irving L.; Crawford, Fred A.; Austin, Erle H.; Oller, Dale W.; Langham, Max.

In: Annals of surgery, Vol. 239, No. 5, 01.05.2004, p. 588-598.

Research output: Contribution to journalArticle

Dibardino, DJ, Allison, AE, Vaughn, WK, McKenzie, ED, Fraser, CD, Kron, IL, Crawford, FA, Austin, EH, Oller, DW & Langham, M 2004, 'Current Expectations for Newborns Undergoing the Arterial Switch Operation', Annals of surgery, vol. 239, no. 5, pp. 588-598. https://doi.org/10.1097/01.sla.0000124293.52814.a7
Dibardino DJ, Allison AE, Vaughn WK, McKenzie ED, Fraser CD, Kron IL et al. Current Expectations for Newborns Undergoing the Arterial Switch Operation. Annals of surgery. 2004 May 1;239(5):588-598. https://doi.org/10.1097/01.sla.0000124293.52814.a7
Dibardino, Daniel J. ; Allison, Andrew E. ; Vaughn, William K. ; McKenzie, E. Dean ; Fraser, Charles D. ; Kron, Irving L. ; Crawford, Fred A. ; Austin, Erle H. ; Oller, Dale W. ; Langham, Max. / Current Expectations for Newborns Undergoing the Arterial Switch Operation. In: Annals of surgery. 2004 ; Vol. 239, No. 5. pp. 588-598.
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abstract = "Background: The arterial switch operation (ASO) represents a remarkable success story in the surgical treatment of cyanotic congenital heart disease. This study is designed to assess recent outcomes after the ASO in babies presenting with transposition of the great arteries (TGA) and Taussig-Bing anomaly (TBA). Methods: One hundred twenty-five consecutive neonatal and infant ASOs were performed by 2 surgeons at Texas Children's Hospital between July 1, 1995 and October 1, 2003. Patients with TGA and TBA were offered ASO irrespective of patient size and associated cardiac malformations. Primary cardiac diagnoses included TGA with intact ventricular septum (TGA/IVS, n = 79, 63{\%}), TGA with ventricular septal defect (TGA/VSD, n = 37, 30{\%}), and Taussig Bing Anomaly (TBA, n = 9, 7{\%}). Results: With complete follow-up, we observed a 30-day mortality rate of 1.6{\%} (n = 2) with 2 late deaths (1.6{\%}), for an overall actuarial survival rate of 96.3{\%} at 7 years. Although there was a significant incidence of complex coronary ostial origin and branching including single coronary (n = 8, 6.4{\%}) and intramural coronary artery (n = 8, 6.4{\%}), this was not associated with increased operative risk. All patients are fully saturated and NYHA functional class I at latest clinic visit (0.3 to 88.4 months postoperatively). There have been no late coronary events. Of 121 survivors, 7 patients (5.8{\%}) have required cardiovascular reoperation at an average of 15.3 ± 11.7 months postoperatively (range, 3.6 to 30.6 months) for an actuarial freedom from reoperation of 90{\%} at 7 years. Conclusions: Using current methodologies, the ASO can be performed safely and with a low incidence of need for reoperation on intermediate follow-up. Recent experience indicates operative survival rates approaching 100{\%}.",
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AU - Allison, Andrew E.

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AU - Fraser, Charles D.

AU - Kron, Irving L.

AU - Crawford, Fred A.

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N2 - Background: The arterial switch operation (ASO) represents a remarkable success story in the surgical treatment of cyanotic congenital heart disease. This study is designed to assess recent outcomes after the ASO in babies presenting with transposition of the great arteries (TGA) and Taussig-Bing anomaly (TBA). Methods: One hundred twenty-five consecutive neonatal and infant ASOs were performed by 2 surgeons at Texas Children's Hospital between July 1, 1995 and October 1, 2003. Patients with TGA and TBA were offered ASO irrespective of patient size and associated cardiac malformations. Primary cardiac diagnoses included TGA with intact ventricular septum (TGA/IVS, n = 79, 63%), TGA with ventricular septal defect (TGA/VSD, n = 37, 30%), and Taussig Bing Anomaly (TBA, n = 9, 7%). Results: With complete follow-up, we observed a 30-day mortality rate of 1.6% (n = 2) with 2 late deaths (1.6%), for an overall actuarial survival rate of 96.3% at 7 years. Although there was a significant incidence of complex coronary ostial origin and branching including single coronary (n = 8, 6.4%) and intramural coronary artery (n = 8, 6.4%), this was not associated with increased operative risk. All patients are fully saturated and NYHA functional class I at latest clinic visit (0.3 to 88.4 months postoperatively). There have been no late coronary events. Of 121 survivors, 7 patients (5.8%) have required cardiovascular reoperation at an average of 15.3 ± 11.7 months postoperatively (range, 3.6 to 30.6 months) for an actuarial freedom from reoperation of 90% at 7 years. Conclusions: Using current methodologies, the ASO can be performed safely and with a low incidence of need for reoperation on intermediate follow-up. Recent experience indicates operative survival rates approaching 100%.

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