Current management of Coats disease

Eric J. Sigler, John C. Randolph, Jorge I. Calzada, Matthew Wilson, Barrett G. Haik

Research output: Contribution to journalReview article

45 Citations (Scopus)

Abstract

Since its original description in 1908, Coats disease has been recognized as an idiopathic cause of severe vision loss with a remarkable diversity in clinical presentation and morphology. Key clinical and imaging variables are helpful in differentiating Coats disease from life-threatening malignancies, and proper management revolves around a thorough knowledge of the differential diagnosis. Despite significant advancement in scientific understanding of the disease process and clinical spectrum, the underlying etiology remains obscure, and both primary and secondary forms are recognized. With the development of anti-VEGF therapy, vitreoretinal specialists have a new, effective adjunct to the clinical management of exudates, macular edema, and serous retinal detachment. We highlight the history, diagnostic challenges, evolving clinical spectrum, and current management of Coats disease.

Original languageEnglish (US)
Pages (from-to)30-46
Number of pages17
JournalSurvey of Ophthalmology
Volume59
Issue number1
DOIs
StatePublished - Jan 1 2014

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Retinal Telangiectasis
Macular Edema
Retinal Detachment
Exudates and Transudates
Vascular Endothelial Growth Factor A
Differential Diagnosis
History
Neoplasms
Therapeutics

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Sigler, E. J., Randolph, J. C., Calzada, J. I., Wilson, M., & Haik, B. G. (2014). Current management of Coats disease. Survey of Ophthalmology, 59(1), 30-46. https://doi.org/10.1016/j.survophthal.2013.03.007

Current management of Coats disease. / Sigler, Eric J.; Randolph, John C.; Calzada, Jorge I.; Wilson, Matthew; Haik, Barrett G.

In: Survey of Ophthalmology, Vol. 59, No. 1, 01.01.2014, p. 30-46.

Research output: Contribution to journalReview article

Sigler, EJ, Randolph, JC, Calzada, JI, Wilson, M & Haik, BG 2014, 'Current management of Coats disease', Survey of Ophthalmology, vol. 59, no. 1, pp. 30-46. https://doi.org/10.1016/j.survophthal.2013.03.007
Sigler, Eric J. ; Randolph, John C. ; Calzada, Jorge I. ; Wilson, Matthew ; Haik, Barrett G. / Current management of Coats disease. In: Survey of Ophthalmology. 2014 ; Vol. 59, No. 1. pp. 30-46.
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