Deep venous thrombosis in gynecological oncology

Incidence and clinical symptoms study

Joseph Santoso, Leslie Evans, Lauren Lambrecht, Jim Wan

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Objective: Cancer patients have increased risks of leg deep venous thrombosis (DVT). We studied the incidence, risk factors and most predictive symptoms of leg DVT in gynecologic oncology patients. Study designs: Gynecologic oncology patients with any leg DVT symptoms were recruited and screened using Doppler sonogram. All hospitalized surgery and non-ambulating patients received thigh-high sequential compression devices (SCDs) without heparin as a prophylactic method against thrombosis. Statistical analysis was done using chi-square or Fisher's exact tests. Results: Out of 1974 patients, 134 complained of lower limb symptoms. Doppler studies found 38 patients with leg DVT. Incidence of leg DVT was 36/853 (4.2%) in patients with cancer and 2/1121 (0.2%) in patients without cancer (odds ratio 2.8 with a diagnosis of cancer). Leg edema, erythema, fever, and warm leg were significant symptoms in diagnosing leg DVT (p < 0.01). The cost of finding a leg DVT was $747.54. Conclusions: Clinical exam is less accurate than Doppler sonogram in diagnosing leg DVT. The incidence of leg DVT using SCD seems to be comparable with other studies. Finally, the cost of identifying leg DVT seems reasonable.

Original languageEnglish (US)
Pages (from-to)173-176
Number of pages4
JournalEuropean Journal of Obstetrics Gynecology and Reproductive Biology
Volume144
Issue number2
DOIs
StatePublished - Jun 1 2009

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Venous Thrombosis
Leg
Incidence
Clinical Studies
Neoplasms
Costs and Cost Analysis
Equipment and Supplies
Erythema
Thigh
Heparin
Lower Extremity
Edema
Thrombosis
Fever
Odds Ratio

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this

Deep venous thrombosis in gynecological oncology : Incidence and clinical symptoms study. / Santoso, Joseph; Evans, Leslie; Lambrecht, Lauren; Wan, Jim.

In: European Journal of Obstetrics Gynecology and Reproductive Biology, Vol. 144, No. 2, 01.06.2009, p. 173-176.

Research output: Contribution to journalArticle

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