Defining the components of the research pipeline

Michael Kleinman, James W. Mold

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The National Institutes of Health (NIH) has proposed that research moves from "bench to bedside" through a Pipeline consisting of distinct research categories bridged by bidirectional translation. The original NIH Pipeline has now been expanded to include practice- and community-based research. We developed operational definitions for the elements along the expanded NIH Pipeline. The proposed definitions were pilot-tested and refined using the Computer Retrieval of Information on Scientific Projects (CRISP) and the Secure Internet-Linked Web Technologies (SILK) database containing funding information for individual NIH awards. Using our definitions, two reviewers independently agreed on the categorization of 94% of 866 National Heart, Lung, and Blood Institute (NHLBI)-funded projects, and 99% of projects could be placed into a single research category.

Original languageEnglish (US)
Pages (from-to)312-314
Number of pages3
JournalClinical and Translational Science
Volume2
Issue number4
DOIs
StatePublished - Aug 28 2009

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National Institutes of Health (U.S.)
Pipelines
Health
Research
National Heart, Lung, and Blood Institute (U.S.)
Information Storage and Retrieval
Internet
Blood
Databases
Technology

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Defining the components of the research pipeline. / Kleinman, Michael; Mold, James W.

In: Clinical and Translational Science, Vol. 2, No. 4, 28.08.2009, p. 312-314.

Research output: Contribution to journalArticle

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