Dermatological Disorders in Parkinson's Disease

Robert B. Skinner, Mark Ledoux

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

The first suggestion of an increased risk of melanoma in Parkinson disease (PD) patients was reported by Skibba et al. (Arch Pathol 93:556-561, 1972) in 1972. They reported a 55-year-old male with PD who developed a local recurrence of a primary melanoma and multiple primary melanomas 4 years after primary excision and 4 months after starting levodopa. Since levodopa is a metabolite in the biosynthesis of dopamine and melanin involving the enzyme tyrosinase, and increased tyrosinase activity is found in melanoma, they speculated that levodopa "could enhance and stimulate growth on any residual melanoma tissue".

Original languageEnglish (US)
Title of host publicationParkinson's Disease and Nonmotor Dysfunction
PublisherHumana Press Inc.
Pages237-242
Number of pages6
ISBN (Print)9781607614289
StatePublished - Jan 1 2013

Publication series

NameCurrent Clinical Neurology
Volume24
ISSN (Print)1559-0585

Fingerprint

Parkinson Disease
Melanoma
Levodopa
Monophenol Monooxygenase
Recurrence
Enzymes
Growth

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Skinner, R. B., & Ledoux, M. (2013). Dermatological Disorders in Parkinson's Disease. In Parkinson's Disease and Nonmotor Dysfunction (pp. 237-242). (Current Clinical Neurology; Vol. 24). Humana Press Inc..

Dermatological Disorders in Parkinson's Disease. / Skinner, Robert B.; Ledoux, Mark.

Parkinson's Disease and Nonmotor Dysfunction. Humana Press Inc., 2013. p. 237-242 (Current Clinical Neurology; Vol. 24).

Research output: Chapter in Book/Report/Conference proceedingChapter

Skinner, RB & Ledoux, M 2013, Dermatological Disorders in Parkinson's Disease. in Parkinson's Disease and Nonmotor Dysfunction. Current Clinical Neurology, vol. 24, Humana Press Inc., pp. 237-242.
Skinner RB, Ledoux M. Dermatological Disorders in Parkinson's Disease. In Parkinson's Disease and Nonmotor Dysfunction. Humana Press Inc. 2013. p. 237-242. (Current Clinical Neurology).
Skinner, Robert B. ; Ledoux, Mark. / Dermatological Disorders in Parkinson's Disease. Parkinson's Disease and Nonmotor Dysfunction. Humana Press Inc., 2013. pp. 237-242 (Current Clinical Neurology).
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