Design and synthesis of (E)-1-((3-ethyl-2,4,4-trimethylcyclohex-2- enylidene)methyl-4-substituted benzenes from 1-(2,6,6-trimethylcyclohex-1-enyl) ethanol

Bhaskar C. Das, Sakkarapalayam M. Mahalingam, Todd Evans, George Kabalka, J. Anguiano, K. Hema

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A novel strategy for synthesizing (E)-1-((3-ethyl-2,4,4-trimethylcyclohex- 2-enylidene)methyl-4-substituted benzenes from 1-(2,6,6-trimethylcyclohex-1- enyl)ethanol 3 has been developed; the allylic alcohol 3 was treated with PPh3·HBr in methanol followed by aldehydes in the presence of a base and furnished the 1,3-dienes in moderate to good yields (79-86%).

Original languageEnglish (US)
Pages (from-to)2133-2135
Number of pages3
JournalChemical Communications
Issue number16
DOIs
StatePublished - Apr 20 2009
Externally publishedYes

Fingerprint

Benzene
Aldehydes
Methanol
Alcohols
Ethanol
allyl alcohol
1-(2,6,6-trimethylcyclohex-1-enyl)ethanol

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Design and synthesis of (E)-1-((3-ethyl-2,4,4-trimethylcyclohex-2- enylidene)methyl-4-substituted benzenes from 1-(2,6,6-trimethylcyclohex-1-enyl) ethanol. / Das, Bhaskar C.; Mahalingam, Sakkarapalayam M.; Evans, Todd; Kabalka, George; Anguiano, J.; Hema, K.

In: Chemical Communications, No. 16, 20.04.2009, p. 2133-2135.

Research output: Contribution to journalArticle

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