Detection of Loss of Cerebral Vascular Tone by Correlation of Arterial and Intracranial Pressure Signals

Michael L. Daley, Harikrishnan Pasupathy, Michael Griffith, James T. Robertson, Charles Leffler

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

With the use of a laboratory model, arterial and intracranial pressure signals were obtained under conditions of intact regulation of cerebral blood flow and massive dilation. During elevated intracranial pressure and intact regulation, positive pressure inhalation appears to briefly occlude venous flow into the cranial sinuses during inspiration. As a result, the intracranial pressure and arterial pressure signals are not similar. In contrast, when maximal dilation causes failure of regulation of cerebral blood flow, the intracranial pressure signal is approximately proportional to the arterial pressure signal. Comparison of the crosscorrelation function derived from the intracranial and arterial pressure signals to the autocorrelation function of the arterial signal reveals that the two correlation functions are: 1) different during intact regulation and 2) nearly identical during dilation induced failure of regulation of cerebral blood flow.

Original languageEnglish (US)
Pages (from-to)420-424
Number of pages5
JournalIEEE Transactions on Biomedical Engineering
Volume42
Issue number4
DOIs
StatePublished - Jan 1 1995

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Blood
Autocorrelation

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

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Detection of Loss of Cerebral Vascular Tone by Correlation of Arterial and Intracranial Pressure Signals. / Daley, Michael L.; Pasupathy, Harikrishnan; Griffith, Michael; Robertson, James T.; Leffler, Charles.

In: IEEE Transactions on Biomedical Engineering, Vol. 42, No. 4, 01.01.1995, p. 420-424.

Research output: Contribution to journalArticle

Daley, Michael L. ; Pasupathy, Harikrishnan ; Griffith, Michael ; Robertson, James T. ; Leffler, Charles. / Detection of Loss of Cerebral Vascular Tone by Correlation of Arterial and Intracranial Pressure Signals. In: IEEE Transactions on Biomedical Engineering. 1995 ; Vol. 42, No. 4. pp. 420-424.
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