Dilated cardiomyopathy

A tale of cytoskeletal proteins and beyond

Jeffrey Towbin, Neil E. Bowles

Research output: Contribution to journalReview article

38 Citations (Scopus)

Abstract

DCM occurs due to disruption of the cytoskeleton and its linkage to the sarcomere and nucleus. Treatment approaches in the future should consider targeting these proteins and the secondary abnormalities caused by mechanical stress. Once these approaches are adopted, new studies in the treatment of these disorders will be possible.

Original languageEnglish (US)
Pages (from-to)919-926
Number of pages8
JournalJournal of Cardiovascular Electrophysiology
Volume17
Issue number8
DOIs
StatePublished - Aug 1 2006
Externally publishedYes

Fingerprint

Sarcomeres
Mechanical Stress
Cytoskeletal Proteins
Dilated Cardiomyopathy
Protein Transport
Cytoskeleton

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Dilated cardiomyopathy : A tale of cytoskeletal proteins and beyond. / Towbin, Jeffrey; Bowles, Neil E.

In: Journal of Cardiovascular Electrophysiology, Vol. 17, No. 8, 01.08.2006, p. 919-926.

Research output: Contribution to journalReview article

@article{9394fe25a55947f69577fba0eb611ef2,
title = "Dilated cardiomyopathy: A tale of cytoskeletal proteins and beyond",
abstract = "DCM occurs due to disruption of the cytoskeleton and its linkage to the sarcomere and nucleus. Treatment approaches in the future should consider targeting these proteins and the secondary abnormalities caused by mechanical stress. Once these approaches are adopted, new studies in the treatment of these disorders will be possible.",
author = "Jeffrey Towbin and Bowles, {Neil E.}",
year = "2006",
month = "8",
day = "1",
doi = "10.1111/j.1540-8167.2006.00530.x",
language = "English (US)",
volume = "17",
pages = "919--926",
journal = "Journal of Cardiovascular Electrophysiology",
issn = "1045-3873",
publisher = "Wiley-Blackwell",
number = "8",

}

TY - JOUR

T1 - Dilated cardiomyopathy

T2 - A tale of cytoskeletal proteins and beyond

AU - Towbin, Jeffrey

AU - Bowles, Neil E.

PY - 2006/8/1

Y1 - 2006/8/1

N2 - DCM occurs due to disruption of the cytoskeleton and its linkage to the sarcomere and nucleus. Treatment approaches in the future should consider targeting these proteins and the secondary abnormalities caused by mechanical stress. Once these approaches are adopted, new studies in the treatment of these disorders will be possible.

AB - DCM occurs due to disruption of the cytoskeleton and its linkage to the sarcomere and nucleus. Treatment approaches in the future should consider targeting these proteins and the secondary abnormalities caused by mechanical stress. Once these approaches are adopted, new studies in the treatment of these disorders will be possible.

UR - http://www.scopus.com/inward/record.url?scp=33746038182&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33746038182&partnerID=8YFLogxK

U2 - 10.1111/j.1540-8167.2006.00530.x

DO - 10.1111/j.1540-8167.2006.00530.x

M3 - Review article

VL - 17

SP - 919

EP - 926

JO - Journal of Cardiovascular Electrophysiology

JF - Journal of Cardiovascular Electrophysiology

SN - 1045-3873

IS - 8

ER -