Disorders of left ventricular trabeculation/compaction or right ventricular wall formation

Joseph T C Shieh, John Jefferies, Alvin J. Chin

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Cardiomyopathies are remarkably variable in form. Although hearts may be dilated or hypertrophic, the spectrum of cardiomyopathies includes left ventricular noncompaction/hypertrabeculation and right ventricular wall disorders. These conditions have been increasingly recognized in patients given advances in clinical diagnostics. Here we present information on cardiac pathophysiology, from ventricular wall formation and trabeculae in model organisms to pediatric and adult disease. Many genes to affect the ventricular phenotype, and this has implications for deciphering developmental and disease pathways and for applying testing for clinical care.

Original languageEnglish (US)
Pages (from-to)141-143
Number of pages3
JournalAmerican Journal of Medical Genetics, Part C: Seminars in Medical Genetics
Volume163
Issue number3
DOIs
StatePublished - Aug 1 2013
Externally publishedYes

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Hypertrophic Cardiomyopathy
Cardiomyopathies
Pediatrics
Phenotype
Genes

All Science Journal Classification (ASJC) codes

  • Genetics
  • Genetics(clinical)

Cite this

Disorders of left ventricular trabeculation/compaction or right ventricular wall formation. / Shieh, Joseph T C; Jefferies, John; Chin, Alvin J.

In: American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, Vol. 163, No. 3, 01.08.2013, p. 141-143.

Research output: Contribution to journalArticle

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