Distribution of choline acetyltransferase immunoreactivity in the pigeon brain

Loreta Medina, Anton Reiner

Research output: Contribution to journalArticle

177 Citations (Scopus)

Abstract

We have investigated the distribution of cholinergic perikarya and fibers in the brain of the pigeon (Columba livia). With this aim, pigeon brain sections were processed immunohistochemi‐cally by using an antiserum specific for chicken choline acetyltransferase. Our results show cholinergic neurons in the pigeon basal telencephalon, the hypothalamus, the habenula, the pretectum, the midbrain tectum, the dorsal isthmus, the isthmic tegmentum, and the cranial nerve motor nuclei. Cholinergic fibers were prominent in the dorsal telencephalon, the striatum, the thalamus, the tectum, and the interpeduncular nucleus. Comparison of our results with previous studies in birds suggests some major cholinergic pathways in the avian brain and clarifies the possible origin of the cholinergic innervation of some parts of the avian brain. In addition, comparison of our results in birds with those in other vertebrate species shows that the organization of the cholinergic systems in many regions of the avian brain (such as the basal forebrain, the epithalamus, the isthmus, and the hindbrain) is much like that in reptiles and mammals. In contrast, however, birds appear largely to lack intrinsic cholinergic neurons in the dorsal (“neocortex‐like”) parts of the telencephalon. © 1994 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)497-537
Number of pages41
JournalJournal of Comparative Neurology
Volume342
Issue number4
DOIs
StatePublished - Jan 1 1994

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Choline O-Acetyltransferase
Columbidae
Telencephalon
Cholinergic Fibers
Cholinergic Agents
Brain
Birds
Cholinergic Neurons
Epithalamus
Habenula
Rhombencephalon
Reptiles
Cranial Nerves
Mesencephalon
Thalamus
Hypothalamus
Vertebrates
Immune Sera
Mammals
Chickens

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Distribution of choline acetyltransferase immunoreactivity in the pigeon brain. / Medina, Loreta; Reiner, Anton.

In: Journal of Comparative Neurology, Vol. 342, No. 4, 01.01.1994, p. 497-537.

Research output: Contribution to journalArticle

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