Distribution of nicotinic binding sites with respect to CRF and neurophysin immunoreactive perikarya within the rat hypothalamus

Burt Sharp, S. Nicol, S. Cummings, V. Seybold

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

These studies determined the differential autoradiographic distribution of [125I]α-bungarotoxin versus [3H]nicotine relative to the histochemically defined perikarya for neurophysin and corticotropin releasing factor (CRF). Specific [3H]nicotine binding sites occured in relatively greater density within the neuropil surrounding PVN and SON compared to within the nuclei. In contrast, the highest density of [125I]α-BTX sites codistributed with neurophysin immunoreactive perikarya within these nuclei.

Original languageEnglish (US)
Pages (from-to)361-366
Number of pages6
JournalBrain Research
Volume422
Issue number2
DOIs
StatePublished - Oct 6 1987

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Neurophysins
Corticotropin-Releasing Hormone
Nicotine
Hypothalamus
Binding Sites
Bungarotoxins
Neuropil

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Cite this

Distribution of nicotinic binding sites with respect to CRF and neurophysin immunoreactive perikarya within the rat hypothalamus. / Sharp, Burt; Nicol, S.; Cummings, S.; Seybold, V.

In: Brain Research, Vol. 422, No. 2, 06.10.1987, p. 361-366.

Research output: Contribution to journalArticle

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