Diurnal and seasonal variation of stroke incidence in patients with cardioembolic stroke due to atrial fibrillation

Konstantinos Spengos, Konstantinos Vemmos, Georgios Tsivgoulis, Efstathios Manios, Nikolaos Zakopoulos, Myron Mavrikakis, Demitris Vassilopoulos

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

A seasonal variation with an incidence peak during the colder period of the year, as well as a circadian distribution with a single peak of stroke onset in the morning hours are described in various countries. Cardioembolic stroke seems to be the most frequent stroke subtype among Greek patients. Atrial fibrillation is identified as the most frequent cause of stroke. Analysis of the temporal pattern of symptom onset in a series of over 300 Greek patients with first-ever cardioembolic acute stroke due to atrial fibrillation revealed a circannual distribution with a peak during winter and a decline of stroke occurrence during summer. Analysis of the diurnal variation of symptom onset in this stroke subgroup showed a distribution with 2 incidence peaks between 08:00-10:00 and 16:00-18:00. A relation between the second, however lower, frequency peak and the traditional Greek habit of afternoon sleep (siesta) could be assumed. Possible clustering of cardiologic events in patients with atrial fibrillation, especially during the time interval after awakening from night and afternoon sleep, could be a plausible explanation, which certainly deserves to be further investigated.

Original languageEnglish (US)
Pages (from-to)204-210
Number of pages7
JournalNeuroepidemiology
Volume22
Issue number3
DOIs
StatePublished - May 6 2003

Fingerprint

Atrial Fibrillation
Stroke
Incidence
Sleep
Habits
Cluster Analysis

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Clinical Neurology

Cite this

Diurnal and seasonal variation of stroke incidence in patients with cardioembolic stroke due to atrial fibrillation. / Spengos, Konstantinos; Vemmos, Konstantinos; Tsivgoulis, Georgios; Manios, Efstathios; Zakopoulos, Nikolaos; Mavrikakis, Myron; Vassilopoulos, Demitris.

In: Neuroepidemiology, Vol. 22, No. 3, 06.05.2003, p. 204-210.

Research output: Contribution to journalArticle

Spengos, K, Vemmos, K, Tsivgoulis, G, Manios, E, Zakopoulos, N, Mavrikakis, M & Vassilopoulos, D 2003, 'Diurnal and seasonal variation of stroke incidence in patients with cardioembolic stroke due to atrial fibrillation', Neuroepidemiology, vol. 22, no. 3, pp. 204-210. https://doi.org/10.1159/000069897
Spengos, Konstantinos ; Vemmos, Konstantinos ; Tsivgoulis, Georgios ; Manios, Efstathios ; Zakopoulos, Nikolaos ; Mavrikakis, Myron ; Vassilopoulos, Demitris. / Diurnal and seasonal variation of stroke incidence in patients with cardioembolic stroke due to atrial fibrillation. In: Neuroepidemiology. 2003 ; Vol. 22, No. 3. pp. 204-210.
@article{1229dee7eff64eea86a5555ad8a430b0,
title = "Diurnal and seasonal variation of stroke incidence in patients with cardioembolic stroke due to atrial fibrillation",
abstract = "A seasonal variation with an incidence peak during the colder period of the year, as well as a circadian distribution with a single peak of stroke onset in the morning hours are described in various countries. Cardioembolic stroke seems to be the most frequent stroke subtype among Greek patients. Atrial fibrillation is identified as the most frequent cause of stroke. Analysis of the temporal pattern of symptom onset in a series of over 300 Greek patients with first-ever cardioembolic acute stroke due to atrial fibrillation revealed a circannual distribution with a peak during winter and a decline of stroke occurrence during summer. Analysis of the diurnal variation of symptom onset in this stroke subgroup showed a distribution with 2 incidence peaks between 08:00-10:00 and 16:00-18:00. A relation between the second, however lower, frequency peak and the traditional Greek habit of afternoon sleep (siesta) could be assumed. Possible clustering of cardiologic events in patients with atrial fibrillation, especially during the time interval after awakening from night and afternoon sleep, could be a plausible explanation, which certainly deserves to be further investigated.",
author = "Konstantinos Spengos and Konstantinos Vemmos and Georgios Tsivgoulis and Efstathios Manios and Nikolaos Zakopoulos and Myron Mavrikakis and Demitris Vassilopoulos",
year = "2003",
month = "5",
day = "6",
doi = "10.1159/000069897",
language = "English (US)",
volume = "22",
pages = "204--210",
journal = "Neuroepidemiology",
issn = "0251-5350",
publisher = "S. Karger AG",
number = "3",

}

TY - JOUR

T1 - Diurnal and seasonal variation of stroke incidence in patients with cardioembolic stroke due to atrial fibrillation

AU - Spengos, Konstantinos

AU - Vemmos, Konstantinos

AU - Tsivgoulis, Georgios

AU - Manios, Efstathios

AU - Zakopoulos, Nikolaos

AU - Mavrikakis, Myron

AU - Vassilopoulos, Demitris

PY - 2003/5/6

Y1 - 2003/5/6

N2 - A seasonal variation with an incidence peak during the colder period of the year, as well as a circadian distribution with a single peak of stroke onset in the morning hours are described in various countries. Cardioembolic stroke seems to be the most frequent stroke subtype among Greek patients. Atrial fibrillation is identified as the most frequent cause of stroke. Analysis of the temporal pattern of symptom onset in a series of over 300 Greek patients with first-ever cardioembolic acute stroke due to atrial fibrillation revealed a circannual distribution with a peak during winter and a decline of stroke occurrence during summer. Analysis of the diurnal variation of symptom onset in this stroke subgroup showed a distribution with 2 incidence peaks between 08:00-10:00 and 16:00-18:00. A relation between the second, however lower, frequency peak and the traditional Greek habit of afternoon sleep (siesta) could be assumed. Possible clustering of cardiologic events in patients with atrial fibrillation, especially during the time interval after awakening from night and afternoon sleep, could be a plausible explanation, which certainly deserves to be further investigated.

AB - A seasonal variation with an incidence peak during the colder period of the year, as well as a circadian distribution with a single peak of stroke onset in the morning hours are described in various countries. Cardioembolic stroke seems to be the most frequent stroke subtype among Greek patients. Atrial fibrillation is identified as the most frequent cause of stroke. Analysis of the temporal pattern of symptom onset in a series of over 300 Greek patients with first-ever cardioembolic acute stroke due to atrial fibrillation revealed a circannual distribution with a peak during winter and a decline of stroke occurrence during summer. Analysis of the diurnal variation of symptom onset in this stroke subgroup showed a distribution with 2 incidence peaks between 08:00-10:00 and 16:00-18:00. A relation between the second, however lower, frequency peak and the traditional Greek habit of afternoon sleep (siesta) could be assumed. Possible clustering of cardiologic events in patients with atrial fibrillation, especially during the time interval after awakening from night and afternoon sleep, could be a plausible explanation, which certainly deserves to be further investigated.

UR - http://www.scopus.com/inward/record.url?scp=0344951183&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0344951183&partnerID=8YFLogxK

U2 - 10.1159/000069897

DO - 10.1159/000069897

M3 - Article

VL - 22

SP - 204

EP - 210

JO - Neuroepidemiology

JF - Neuroepidemiology

SN - 0251-5350

IS - 3

ER -