Do smoking reduction interventions promote cessation in smokers not ready to quit?

Taghrid Asfar, Jon O. Ebbert, Robert Klesges, George E. Relyea

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

Background: Limited treatment options exist for smokers who are not ready to make a quit attempt. Smoking reduction may be a viable treatment approach if proven to increase the rates of long-term abstinence from smoking. Method: A systematic review of randomized, controlled trials that tested smoking-reduction interventions (pharmacological, behavioral, or both combined) among smokers who were not ready to make a quit attempt (immediately or in the next month) was conducted to assess the efficacy of these strategies in promoting future smoking abstinence. The primary outcome was the 7-day point-prevalence smoking abstinence at longest follow-up (≥ 6. months). Ten trials were included; six tested pharmacologic interventions, one evaluated a behavioral intervention, and three evaluated combined interventions. Results: Pharmacologic (2732 participants; OR 2.33, 95% CI 1.43 to 3.79) and combined (638 participants; OR 2.14, 95% CI: 1.28 to 3.60) smoking-reduction interventions significantly increased long-term abstinence from smoking. Insufficient evidence was available on the efficacy of behavioral smoking-reduction interventions (320 participants; OR 1.49, 95% CI 0.56 to 3.93). Conclusions: Further research to evaluate the efficacy of smoking reduction should have cessation as an endpoint, focus on clarity and consistency in patient selection, and identify the mechanism through which nicotine replacement therapy assisted smoking reduction in increasing abstinence rates.

Original languageEnglish (US)
Pages (from-to)764-768
Number of pages5
JournalAddictive Behaviors
Volume36
Issue number7
DOIs
StatePublished - Jul 1 2011

Fingerprint

Smoking
Nicotine
Patient Selection
Randomized Controlled Trials
Pharmacology
Research

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Clinical Psychology
  • Toxicology
  • Psychiatry and Mental health

Cite this

Do smoking reduction interventions promote cessation in smokers not ready to quit? / Asfar, Taghrid; Ebbert, Jon O.; Klesges, Robert; Relyea, George E.

In: Addictive Behaviors, Vol. 36, No. 7, 01.07.2011, p. 764-768.

Research output: Contribution to journalArticle

Asfar, Taghrid ; Ebbert, Jon O. ; Klesges, Robert ; Relyea, George E. / Do smoking reduction interventions promote cessation in smokers not ready to quit?. In: Addictive Behaviors. 2011 ; Vol. 36, No. 7. pp. 764-768.
@article{fd506e69bdcc48c7b7d40cc2a71f580f,
title = "Do smoking reduction interventions promote cessation in smokers not ready to quit?",
abstract = "Background: Limited treatment options exist for smokers who are not ready to make a quit attempt. Smoking reduction may be a viable treatment approach if proven to increase the rates of long-term abstinence from smoking. Method: A systematic review of randomized, controlled trials that tested smoking-reduction interventions (pharmacological, behavioral, or both combined) among smokers who were not ready to make a quit attempt (immediately or in the next month) was conducted to assess the efficacy of these strategies in promoting future smoking abstinence. The primary outcome was the 7-day point-prevalence smoking abstinence at longest follow-up (≥ 6. months). Ten trials were included; six tested pharmacologic interventions, one evaluated a behavioral intervention, and three evaluated combined interventions. Results: Pharmacologic (2732 participants; OR 2.33, 95{\%} CI 1.43 to 3.79) and combined (638 participants; OR 2.14, 95{\%} CI: 1.28 to 3.60) smoking-reduction interventions significantly increased long-term abstinence from smoking. Insufficient evidence was available on the efficacy of behavioral smoking-reduction interventions (320 participants; OR 1.49, 95{\%} CI 0.56 to 3.93). Conclusions: Further research to evaluate the efficacy of smoking reduction should have cessation as an endpoint, focus on clarity and consistency in patient selection, and identify the mechanism through which nicotine replacement therapy assisted smoking reduction in increasing abstinence rates.",
author = "Taghrid Asfar and Ebbert, {Jon O.} and Robert Klesges and Relyea, {George E.}",
year = "2011",
month = "7",
day = "1",
doi = "10.1016/j.addbeh.2011.02.003",
language = "English (US)",
volume = "36",
pages = "764--768",
journal = "Addictive Behaviors",
issn = "0306-4603",
publisher = "Elsevier Limited",
number = "7",

}

TY - JOUR

T1 - Do smoking reduction interventions promote cessation in smokers not ready to quit?

AU - Asfar, Taghrid

AU - Ebbert, Jon O.

AU - Klesges, Robert

AU - Relyea, George E.

PY - 2011/7/1

Y1 - 2011/7/1

N2 - Background: Limited treatment options exist for smokers who are not ready to make a quit attempt. Smoking reduction may be a viable treatment approach if proven to increase the rates of long-term abstinence from smoking. Method: A systematic review of randomized, controlled trials that tested smoking-reduction interventions (pharmacological, behavioral, or both combined) among smokers who were not ready to make a quit attempt (immediately or in the next month) was conducted to assess the efficacy of these strategies in promoting future smoking abstinence. The primary outcome was the 7-day point-prevalence smoking abstinence at longest follow-up (≥ 6. months). Ten trials were included; six tested pharmacologic interventions, one evaluated a behavioral intervention, and three evaluated combined interventions. Results: Pharmacologic (2732 participants; OR 2.33, 95% CI 1.43 to 3.79) and combined (638 participants; OR 2.14, 95% CI: 1.28 to 3.60) smoking-reduction interventions significantly increased long-term abstinence from smoking. Insufficient evidence was available on the efficacy of behavioral smoking-reduction interventions (320 participants; OR 1.49, 95% CI 0.56 to 3.93). Conclusions: Further research to evaluate the efficacy of smoking reduction should have cessation as an endpoint, focus on clarity and consistency in patient selection, and identify the mechanism through which nicotine replacement therapy assisted smoking reduction in increasing abstinence rates.

AB - Background: Limited treatment options exist for smokers who are not ready to make a quit attempt. Smoking reduction may be a viable treatment approach if proven to increase the rates of long-term abstinence from smoking. Method: A systematic review of randomized, controlled trials that tested smoking-reduction interventions (pharmacological, behavioral, or both combined) among smokers who were not ready to make a quit attempt (immediately or in the next month) was conducted to assess the efficacy of these strategies in promoting future smoking abstinence. The primary outcome was the 7-day point-prevalence smoking abstinence at longest follow-up (≥ 6. months). Ten trials were included; six tested pharmacologic interventions, one evaluated a behavioral intervention, and three evaluated combined interventions. Results: Pharmacologic (2732 participants; OR 2.33, 95% CI 1.43 to 3.79) and combined (638 participants; OR 2.14, 95% CI: 1.28 to 3.60) smoking-reduction interventions significantly increased long-term abstinence from smoking. Insufficient evidence was available on the efficacy of behavioral smoking-reduction interventions (320 participants; OR 1.49, 95% CI 0.56 to 3.93). Conclusions: Further research to evaluate the efficacy of smoking reduction should have cessation as an endpoint, focus on clarity and consistency in patient selection, and identify the mechanism through which nicotine replacement therapy assisted smoking reduction in increasing abstinence rates.

UR - http://www.scopus.com/inward/record.url?scp=79954690874&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79954690874&partnerID=8YFLogxK

U2 - 10.1016/j.addbeh.2011.02.003

DO - 10.1016/j.addbeh.2011.02.003

M3 - Article

VL - 36

SP - 764

EP - 768

JO - Addictive Behaviors

JF - Addictive Behaviors

SN - 0306-4603

IS - 7

ER -