Does mitigating pain decrease the risk of infection? The interactions between nociception and immune function

Linda A. Hatfield, Reba Umberger

Research output: Contribution to journalArticle

Abstract

Recent studies suggest that analgesic interventions may influence immune function and the development of infection in neonates. Although substantial literature exists for the bidirectional relationship between nociception and immune pathways, there is a paucity of rigorous research linking nociception and immune function with the incidence of infection. This article presents the best available evidence for the interactions between nociception, immune function and the development of infection. Rigorous research is urgently needed to determine if anesthetic and analgesic regimens can influence immunomodulation or boost immune function significantly to avert infection.

Original languageEnglish (US)
Pages (from-to)11-17
Number of pages7
JournalJournal of Neonatal Nursing
Volume21
Issue number1
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Fingerprint

Nociception
Pain
Infection
Analgesics
Immunomodulation
Research
Anesthetics
Incidence

All Science Journal Classification (ASJC) codes

  • Maternity and Midwifery

Cite this

Does mitigating pain decrease the risk of infection? The interactions between nociception and immune function. / Hatfield, Linda A.; Umberger, Reba.

In: Journal of Neonatal Nursing, Vol. 21, No. 1, 01.01.2015, p. 11-17.

Research output: Contribution to journalArticle

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