Doppler assessment of the splenic artery blood flow velocity waveforms in the anemic fetus before and after intravascular transfusion

R. Itm D'Ancona, F. Rahman, R. Bahado-Sirigh, J. Copel, Giancarlo Mari

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: To assess flow velocity waveform of the splenic artery (SA) of the anemic fetus prior to and following intrauterine transfusion. STUDY DESIGN: Color guided pulsed Doppler was used to obtain the resistance index (RI) and the peak velocity (PV) from the SA in 10 anemic fetuses that were transfused in utero for Rh-alloimmunization. A paired t-test was used for the statistical analysis. A p < 0.05 was considered statistically significant. RESULTS: Twelve intrauterine transfusions were performed; gestational age ranged from 20 to 34 weeks (mean ±SD: 26 ±4.42 weeks). The hematocrit ranged from 5.9% to 31.2% {mean ±SD: 21.9% ±8.2%) prior to transfusion; whereas, it was between 30.2% and 51.9% (mean ±SD: 45.2% ±7.9%) after transfusion. The splenic artery RI (mean ±SD) was 0.78 ±0.064 prior to transfusion; it was 0.64 ±0.096 after transfusion (p < 0.05). The PV of the splenic artery was 48.5 ±17.5 cm/s before transfusion, and it was 50.12 ±29.4 cm/s following transfusion (p > 0.05). CONCLUSIONS: 1 ) The decrease in splenic arten' RI after transfusion suggests an increased blood flow to the spleen; 2) the lack of a change of the peak velocity of the splenic artery following transfusion suggests that it is not a good indicator of fetal anemia, as has been reported with the middle cerebral artery peak velocity. Ftirther studies are necessary.

Original languageEnglish (US)
JournalActa Diabetologica Latina
Volume176
Issue number1 PART II
StatePublished - 1997
Externally publishedYes

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Splenic Artery
Blood Flow Velocity
Fetus
Intrauterine Blood Transfusion
Middle Cerebral Artery
Anemia
Spleen
Color

All Science Journal Classification (ASJC) codes

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

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Doppler assessment of the splenic artery blood flow velocity waveforms in the anemic fetus before and after intravascular transfusion. / Itm D'Ancona, R.; Rahman, F.; Bahado-Sirigh, R.; Copel, J.; Mari, Giancarlo.

In: Acta Diabetologica Latina, Vol. 176, No. 1 PART II, 1997.

Research output: Contribution to journalArticle

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title = "Doppler assessment of the splenic artery blood flow velocity waveforms in the anemic fetus before and after intravascular transfusion",
abstract = "OBJECTIVE: To assess flow velocity waveform of the splenic artery (SA) of the anemic fetus prior to and following intrauterine transfusion. STUDY DESIGN: Color guided pulsed Doppler was used to obtain the resistance index (RI) and the peak velocity (PV) from the SA in 10 anemic fetuses that were transfused in utero for Rh-alloimmunization. A paired t-test was used for the statistical analysis. A p < 0.05 was considered statistically significant. RESULTS: Twelve intrauterine transfusions were performed; gestational age ranged from 20 to 34 weeks (mean ±SD: 26 ±4.42 weeks). The hematocrit ranged from 5.9{\%} to 31.2{\%} {mean ±SD: 21.9{\%} ±8.2{\%}) prior to transfusion; whereas, it was between 30.2{\%} and 51.9{\%} (mean ±SD: 45.2{\%} ±7.9{\%}) after transfusion. The splenic artery RI (mean ±SD) was 0.78 ±0.064 prior to transfusion; it was 0.64 ±0.096 after transfusion (p < 0.05). The PV of the splenic artery was 48.5 ±17.5 cm/s before transfusion, and it was 50.12 ±29.4 cm/s following transfusion (p > 0.05). CONCLUSIONS: 1 ) The decrease in splenic arten' RI after transfusion suggests an increased blood flow to the spleen; 2) the lack of a change of the peak velocity of the splenic artery following transfusion suggests that it is not a good indicator of fetal anemia, as has been reported with the middle cerebral artery peak velocity. Ftirther studies are necessary.",
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T1 - Doppler assessment of the splenic artery blood flow velocity waveforms in the anemic fetus before and after intravascular transfusion

AU - Itm D'Ancona, R.

AU - Rahman, F.

AU - Bahado-Sirigh, R.

AU - Copel, J.

AU - Mari, Giancarlo

PY - 1997

Y1 - 1997

N2 - OBJECTIVE: To assess flow velocity waveform of the splenic artery (SA) of the anemic fetus prior to and following intrauterine transfusion. STUDY DESIGN: Color guided pulsed Doppler was used to obtain the resistance index (RI) and the peak velocity (PV) from the SA in 10 anemic fetuses that were transfused in utero for Rh-alloimmunization. A paired t-test was used for the statistical analysis. A p < 0.05 was considered statistically significant. RESULTS: Twelve intrauterine transfusions were performed; gestational age ranged from 20 to 34 weeks (mean ±SD: 26 ±4.42 weeks). The hematocrit ranged from 5.9% to 31.2% {mean ±SD: 21.9% ±8.2%) prior to transfusion; whereas, it was between 30.2% and 51.9% (mean ±SD: 45.2% ±7.9%) after transfusion. The splenic artery RI (mean ±SD) was 0.78 ±0.064 prior to transfusion; it was 0.64 ±0.096 after transfusion (p < 0.05). The PV of the splenic artery was 48.5 ±17.5 cm/s before transfusion, and it was 50.12 ±29.4 cm/s following transfusion (p > 0.05). CONCLUSIONS: 1 ) The decrease in splenic arten' RI after transfusion suggests an increased blood flow to the spleen; 2) the lack of a change of the peak velocity of the splenic artery following transfusion suggests that it is not a good indicator of fetal anemia, as has been reported with the middle cerebral artery peak velocity. Ftirther studies are necessary.

AB - OBJECTIVE: To assess flow velocity waveform of the splenic artery (SA) of the anemic fetus prior to and following intrauterine transfusion. STUDY DESIGN: Color guided pulsed Doppler was used to obtain the resistance index (RI) and the peak velocity (PV) from the SA in 10 anemic fetuses that were transfused in utero for Rh-alloimmunization. A paired t-test was used for the statistical analysis. A p < 0.05 was considered statistically significant. RESULTS: Twelve intrauterine transfusions were performed; gestational age ranged from 20 to 34 weeks (mean ±SD: 26 ±4.42 weeks). The hematocrit ranged from 5.9% to 31.2% {mean ±SD: 21.9% ±8.2%) prior to transfusion; whereas, it was between 30.2% and 51.9% (mean ±SD: 45.2% ±7.9%) after transfusion. The splenic artery RI (mean ±SD) was 0.78 ±0.064 prior to transfusion; it was 0.64 ±0.096 after transfusion (p < 0.05). The PV of the splenic artery was 48.5 ±17.5 cm/s before transfusion, and it was 50.12 ±29.4 cm/s following transfusion (p > 0.05). CONCLUSIONS: 1 ) The decrease in splenic arten' RI after transfusion suggests an increased blood flow to the spleen; 2) the lack of a change of the peak velocity of the splenic artery following transfusion suggests that it is not a good indicator of fetal anemia, as has been reported with the middle cerebral artery peak velocity. Ftirther studies are necessary.

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