Drug Use Evaluation of Antibiotics in a Pediatric Teaching Hospital

Kelley Lee, Robert J. Leggiadro, Kelly J. Burch

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

OBJECTIVE: To determine the incidence and type of antibiotic use variances at our institution. DESIGN: Inpatient bacterial culture and susceptibility results were reviewed for 1 week per month. Medication administration records were evaluated to determine whether antibiotic selection was appropriate, given the susceptibility of the organism. Process indicators included use of the least costly antibiotic. as well as appropriate dose, interval, and route of administration. The complete medical record was reviewed for all patients if management did not appear to meet criteria. SETTING: A 225-bed. tertiary-care children's teaching hospital. RESULTS: Thirty-five (8.2%) of 428 patients reviewed over 12 months had a total of 49 variances: failure to treat (3), treatment of contaminant/colonizer (2), use of more costly agent (10), failure to revise therapy (8), inappropriate route (2), inappropriate empiric antibiotic (4), incorrect dose (3), unnecessary multiple antibiotics (6), inappropriate drug (8), and prolonged prophylaxis (3). CONCLUSIONS: Thirty-five patients with 10 types of variances were identified during the study. Follow-up monitoring will assess the impact of educational efforts on the incidence of variances. Specific problem antibiotics have been identified for further audits (Infect Control Hosp Epidemiol 1994;15:710-712).

Original languageEnglish (US)
Pages (from-to)710-712
Number of pages3
JournalInfection Control & Hospital Epidemiology
Volume15
Issue number11
DOIs
StatePublished - Nov 1 1994

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Drug Evaluation
Pediatric Hospitals
Teaching Hospitals
Anti-Bacterial Agents
Incidence
Tertiary Healthcare
Medical Records
Inpatients
Therapeutics
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases
  • Epidemiology
  • Immunology

Cite this

Drug Use Evaluation of Antibiotics in a Pediatric Teaching Hospital. / Lee, Kelley; Leggiadro, Robert J.; Burch, Kelly J.

In: Infection Control & Hospital Epidemiology, Vol. 15, No. 11, 01.11.1994, p. 710-712.

Research output: Contribution to journalArticle

Lee, Kelley ; Leggiadro, Robert J. ; Burch, Kelly J. / Drug Use Evaluation of Antibiotics in a Pediatric Teaching Hospital. In: Infection Control & Hospital Epidemiology. 1994 ; Vol. 15, No. 11. pp. 710-712.
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