Duchenne muscular dystrophy

normal ATP turnover in cultured cells.

I. H. Fox, R. Shefner, G. M. Palmieri, Tulio Bertorini

Research output: Contribution to journalArticle

Abstract

We examined ATP metabolism in cultured muscle cells and fibroblasts from patients with Duchenne dystrophy. ATP and ADP levels were the same in cultured cells from normal subjects and patients and there was no difference in ATP synthesis or degradation. Although there was a significant decrease in radioactively labelled ATP after incubation with deoxyglucose in Duchenne muscle cells, there was no difference in ATP concentration or ADP metabolism.

Original languageEnglish (US)
Pages (from-to)493-499
Number of pages7
JournalAdvances in Experimental Medicine and Biology
Volume195 Pt B
StatePublished - 1986

Fingerprint

Duchenne Muscular Dystrophy
Cultured Cells
Adenosine Triphosphate
Cells
Metabolism
Adenosine Diphosphate
Muscle Cells
Muscle
Deoxyglucose
Fibroblasts
Degradation

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Duchenne muscular dystrophy : normal ATP turnover in cultured cells. / Fox, I. H.; Shefner, R.; Palmieri, G. M.; Bertorini, Tulio.

In: Advances in Experimental Medicine and Biology, Vol. 195 Pt B, 1986, p. 493-499.

Research output: Contribution to journalArticle

@article{01f09c70f0d3459e977b6b0d57d4c423,
title = "Duchenne muscular dystrophy: normal ATP turnover in cultured cells.",
abstract = "We examined ATP metabolism in cultured muscle cells and fibroblasts from patients with Duchenne dystrophy. ATP and ADP levels were the same in cultured cells from normal subjects and patients and there was no difference in ATP synthesis or degradation. Although there was a significant decrease in radioactively labelled ATP after incubation with deoxyglucose in Duchenne muscle cells, there was no difference in ATP concentration or ADP metabolism.",
author = "Fox, {I. H.} and R. Shefner and Palmieri, {G. M.} and Tulio Bertorini",
year = "1986",
language = "English (US)",
volume = "195 Pt B",
pages = "493--499",
journal = "Advances in Experimental Medicine and Biology",
issn = "0065-2598",
publisher = "Springer New York",

}

TY - JOUR

T1 - Duchenne muscular dystrophy

T2 - normal ATP turnover in cultured cells.

AU - Fox, I. H.

AU - Shefner, R.

AU - Palmieri, G. M.

AU - Bertorini, Tulio

PY - 1986

Y1 - 1986

N2 - We examined ATP metabolism in cultured muscle cells and fibroblasts from patients with Duchenne dystrophy. ATP and ADP levels were the same in cultured cells from normal subjects and patients and there was no difference in ATP synthesis or degradation. Although there was a significant decrease in radioactively labelled ATP after incubation with deoxyglucose in Duchenne muscle cells, there was no difference in ATP concentration or ADP metabolism.

AB - We examined ATP metabolism in cultured muscle cells and fibroblasts from patients with Duchenne dystrophy. ATP and ADP levels were the same in cultured cells from normal subjects and patients and there was no difference in ATP synthesis or degradation. Although there was a significant decrease in radioactively labelled ATP after incubation with deoxyglucose in Duchenne muscle cells, there was no difference in ATP concentration or ADP metabolism.

UR - http://www.scopus.com/inward/record.url?scp=0022505317&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022505317&partnerID=8YFLogxK

M3 - Article

VL - 195 Pt B

SP - 493

EP - 499

JO - Advances in Experimental Medicine and Biology

JF - Advances in Experimental Medicine and Biology

SN - 0065-2598

ER -