Duchenne muscular dystrophy

Normal ATP turnover in cultured cells

Irving H. Fox, Rachel Shefner, Genaro M.A. Palmieri, Tulio Bertorini

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We examined ATP metabolism in cultured muscle cells and fibroblasts from patients with Duchenne dystrophy. ATP and ADP levels were the same in cultured cells from normal subjects and patients, and there was no difference in ATP synthesis or degradation. Although there was a significant decrease in radioactively labeled ATP after incubation with deoxyglucose in Duchenne muscle cells, there was no difference in ATP concentration or ADP metabolism.

Original languageEnglish (US)
Pages (from-to)1521-1524
Number of pages4
JournalNeurology
Volume35
Issue number10
StatePublished - Jan 1 1985

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Duchenne Muscular Dystrophy
Cultured Cells
Adenosine Triphosphate
Adenosine Diphosphate
Muscle Cells
Deoxyglucose
Fibroblasts

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Fox, I. H., Shefner, R., Palmieri, G. M. A., & Bertorini, T. (1985). Duchenne muscular dystrophy: Normal ATP turnover in cultured cells. Neurology, 35(10), 1521-1524.

Duchenne muscular dystrophy : Normal ATP turnover in cultured cells. / Fox, Irving H.; Shefner, Rachel; Palmieri, Genaro M.A.; Bertorini, Tulio.

In: Neurology, Vol. 35, No. 10, 01.01.1985, p. 1521-1524.

Research output: Contribution to journalArticle

Fox, IH, Shefner, R, Palmieri, GMA & Bertorini, T 1985, 'Duchenne muscular dystrophy: Normal ATP turnover in cultured cells', Neurology, vol. 35, no. 10, pp. 1521-1524.
Fox IH, Shefner R, Palmieri GMA, Bertorini T. Duchenne muscular dystrophy: Normal ATP turnover in cultured cells. Neurology. 1985 Jan 1;35(10):1521-1524.
Fox, Irving H. ; Shefner, Rachel ; Palmieri, Genaro M.A. ; Bertorini, Tulio. / Duchenne muscular dystrophy : Normal ATP turnover in cultured cells. In: Neurology. 1985 ; Vol. 35, No. 10. pp. 1521-1524.
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